Abstract: A frame and protective enclosure is disclosed for artworks, which is particularly suitable for fragile reliefs and other three-dimensional works. The enclosure comprises a transparent shell secured to a backing board. The shell and board are secured and sealed together in a fashion which tends to protect the artwork from atmospheric contaminants. An improved structure is employed for securing the artwork to the backing board in such fashion that it subsequently can be removed without damage, even if the artwork is a paper sculpture or the like.