Abstract: The present invention is directed to complexes consisting essentially of an isolated MHC component and an autoantigenic peptide associated with the antigen binding site of the MHC component. These complexes are useful in treating autoimmune disease.
Type:
Application
Filed:
July 19, 2002
Publication date:
April 10, 2003
Applicant:
Anergen, Inc. a wholly-owned subsidiary of Corixa Corporation
Inventors:
Brian R. Clark, Somesh D. Sharma, Bernard L. Lerch