Abstract: Provided are the use of poly(N-isopropylacrylamide-co-butyl methacrylate) in preparing an embolism material for blood vessels, an embolism material for blood vessels and the use thereof in preparation of drugs. The embolism material for blood vessels comprises poly(N-isopropylacrylamide-co-butyl methacrylate) and a dispersion medium consisting of an electrolyte, a contrast agent, a pH regulator and water. The concentrations of the polymer, electrolyte and contrast agent are respectively 5-30 mg/ml, 0.1-30 mg/ml and 100-350 mg/ml based on iodine. The embolism material for blood vessels is suitable for embolization therapy of tumors in hypervascular and parenchymal visceral organs.
Type:
Grant
Filed:
December 23, 2016
Date of Patent:
April 5, 2022
Assignee:
ANEW-MED LIFE SCIENCE (WUHAN) CO., LTD
Inventors:
Haixia Sun, Hong Liu, Han Li, Jian Zeng, Shuang Liu, Xin Lu, Juncheng Guo, Binghan Yuan, Ling Li
Abstract: Provided are the use of poly(N-isopropylacrylamide-co-butyl methacrylate) in preparing an embolism material for blood vessels, an embolism material for blood vessels and the use thereof in preparation of drugs. The embolism material for blood vessels comprises poly(N-isopropylacrylamide-co-butyl methacrylate) and a dispersion medium consisting of an electrolyte, a contrast agent, a pH regulator and water. The concentrations of the polymer, electrolyte and contrast agent are respectively 5-30 mg/ml, 0.1-30 mg/ml and 100-350 mg/ml based on iodine. The embolism material for blood vessels is suitable for embolization therapy of tumors in hypervascular and parenchymal visceral organs.
Type:
Application
Filed:
December 23, 2016
Publication date:
August 15, 2019
Applicant:
ANEW-MED LIFE SCIENCE (WUHAN) CO., LTD
Inventors:
Haixia SUN, Hong LIU, Han LI, Jian ZENG, Shuang LIU, Xin LU, Juncheng GUO, Binghan YUAN, Ling LI