Abstract: A self-priming-pump-equipped packaging bottle includes a tubular bottle body containing therein an upper seal assembly, a lower seal assembly, and piston from top to bottom. The upper and lower seal assemblies and the tubular bottle body form a closed material-feeding chamber. The lower seal assembly, the piston, and the tubular bottle body form a closed material-storing chamber. The lower seal assembly primarily has a seal seat with a through hole and an elastic sealing gasket covering the through hole from above. The upper seal assembly has an umbrella-shaped member, a hollow material-feeding column, a support post, and an end sealing cap. The end sealing cap is fixed in the umbrella-shaped member through the support post. The hollow material-feeding column's bottom surface, the support post, and the end sealing cap form a material outlet. The umbrella-shaped member lower end is in interference fit with the seal seat.