Patents Assigned to Anika Research, Inc.
  • Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
    Patent number: 6013679
    Abstract: This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.
    Type: Grant
    Filed: December 5, 1995
    Date of Patent: January 11, 2000
    Assignees: Anika Research, Inc., Research Foundation of State University of New York
    Inventors: Jing-Wen Kuo, David A. Swann, Glenn D. Prestwich
  • Steam-sterilizing solid hyaluronic acid
    Patent number: 5621093
    Abstract: A method for sterilizing solid hyaluronic acid includes autoclaving solid hyaluronic acid, whereby the solid hyaluronic acid is exposed to saturated steam at positive gauge pressure for a period of time that is sufficient to sterilize the solid hyaluronic acid. In one embodiment, autoclaving includes exposing the solid hyaluronic acid to saturated steam at a gauge pressure of about one atmosphere for a period of time between about fifteen and thirty minutes.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 15, 1997
    Assignee: Anika Research, Inc.
    Inventors: David A. Swann, Jing-wen Kuo, Vladimir Pinsky
  • Method for treating myopia
    Patent number: 5443473
    Abstract: A method for treating a myopic eye or eye with other refractive errors is provided. The method includes forming a circular cut in the anterial lamina of the cornea, forming a pocket in the lamella beneath the weakened anterial lamina, and inserting an intrastromal lens within the pocket to alter the radius of curvature of the anterial lamina. Devices for weakening the anterial lamina and for forming the pocket within the lamella are also disclosed.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: August 22, 1995
    Assignee: Anika Research, Inc.
    Inventors: David Miller, Edward Perez
  • Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
    Patent number: 5356883
    Abstract: This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: October 18, 1994
    Assignees: Research Foundation of State University of N.Y., Anika Research, Inc.
    Inventors: Jing-Wen Kuo, David A. Swann, Glenn D. Prestwich