Patents Assigned to Animas Technologies LLC
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Patent number: 7731867Abstract: The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, as well as methods of making, and methods of using such compositions and electrodes. An exemplary ink material comprises a metal catalyst (e.g., platinum black and/or platinum-on-carbon), graphite as a conducting material, a polymer binding material, and an organic solvent. In one aspect, the polymer binding material comprises a polymer binder blend comprising first and second polymers, wherein the first polymer has a glass transition temperature higher than the second polymer. In a second aspect, the polymer binding material comprises a hydrophilic acrylic polymer, copolymer, or terpolymer. The conductive polymer compositions of the present invention may be used, for example, to make electrochemical sensors. Such sensors may be used, for example, in a variety of devices to monitor analyte amount or concentrations in subjects.Type: GrantFiled: January 23, 2007Date of Patent: June 8, 2010Assignee: Animas Technologies, LLCInventors: Huawen Li, Michael J. Tierney
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Patent number: 7699775Abstract: The present invention relates to methods to increase the number of analyte-related signals used to provide analyte measurement values, e.g., when two or more analyte-related signals are used to obtain a single analyte measurement value a “rolling” value based on the two or more signals can be employed. In another aspect, interpolation and/or extrapolation methods are used to estimate unusable, missing or error-associated analyte-related signals. Further, interpolation and extrapolation of values are employed in another aspect of the invention that reduces the incident of failed calibrations. Further, the invention relates to methods, which employ gradients and/or predictive algorithms, to provide an alert related to analyte values exceeding predetermined thresholds.Type: GrantFiled: October 13, 2004Date of Patent: April 20, 2010Assignee: Animas Technologies, LLCInventors: Shashi P. Desai, Timothy C. Dunn, Matthew J. Lesho, Russell O. Potts, Janet A. Tamada, Charles W. Wei
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Publication number: 20100049022Abstract: The present invention relates to a predictive-kinetic method for use with data processing of a sensor-generated signal, as well as, microprocessors and monitoring systems employing such a predictive-kinetic method. Data from a transient region of a signal is used with suitable models and curve-fitting methods to predict the signal that would be measured for the system at the completion of the reaction. The values resulting from data processing of sensor response using the methods of the present invention are less sensitive to measurement variables.Type: ApplicationFiled: October 19, 2009Publication date: February 25, 2010Applicant: Animas Technologies, LLC.Inventors: Norman A. Parris, Russell O. Potts, Michael J. Tierney, Christopher Uhegbu
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Patent number: 7523004Abstract: The present invention comprises one or more microprocessors programmed to execute methods for improving the performance of an analyte monitoring device including prediction of glucose levels in a subject by utilizing a predicted slower-time constant (1/k2). In another aspect of the invention, pre-exponential terms (1/c2) can be used to provide a correction for signal decay (e.g., a Gain Factor). In other aspects, the present invention relates to one or more microprocessors comprising programming to control execution of (i) methods for conditional screening of data points to reduce skipped measurements, (ii) methods for qualifying interpolated/extrapolated analyte measurement values, (iii) various integration methods to obtain maximum integrals of analyte-related signals, as well as analyte monitoring devices comprising such microprocessors.Type: GrantFiled: November 9, 2005Date of Patent: April 21, 2009Assignee: Animas Technologies, LLCInventors: Miroslaw Bartkowiak, Wesley S. Harper, Eray Kulcu, Matthew J. Lesho, Janet A. Tamada
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Patent number: 7519478Abstract: The present invention comprises one or more microprocessors programmed to execute methods for improving the performance of an analyte monitoring device including prediction of glucose levels in a subject by utilizing a predicted slower-time constant (1/k2). In another aspect of the invention, pre-exponential terms (1/c2) can be used to provide a correction for signal decay (e.g., a Gain Factor). In other aspects, the present invention relates to one or more microprocessors comprising programming to control execution of (i) methods for conditional screening of data points to reduce skipped measurements, (ii) methods for qualifying interpolated/extrapolated analyte measurement values, (iii) various integration methods to obtain maximum integrals of analyte-related signals, as well as analyte monitoring devices comprising such microprocessors.Type: GrantFiled: November 9, 2005Date of Patent: April 14, 2009Assignee: Animas Technologies, LLCInventors: Miroslaw Bartkowiak, Wesley S. Harper, Eray Kulcu, Matthew J. Lesho, Janet A. Tamada
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Publication number: 20090076731Abstract: The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.Type: ApplicationFiled: June 30, 2008Publication date: March 19, 2009Applicant: ANIMAS TECHNOLOGIES, LLC.Inventors: Timothy C. Dunn, Yalia Jayalakshmi, Ronald T. Kurnik, Mathew J. Lesho, Jonathan James Oliver, Russell O. Potts, Janet A. Tamada, Steven Richard Warehouse, Charles W. Wei
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Publication number: 20080270039Abstract: The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.Type: ApplicationFiled: June 30, 2008Publication date: October 30, 2008Applicant: Animas Technologies, LLC.Inventors: Timothy C. Dunn, Yalia Jayalakshmi, Ronald T. Kurnik, Matthew J. Lesho, Jonathan James Oliver, Russell O. Potts, Janet A. Tamada, Steven Richard Waterhouse, Charles W. Wei
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Publication number: 20080262746Abstract: The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.Type: ApplicationFiled: June 30, 2008Publication date: October 23, 2008Applicant: Animas Technologies, LLC.Inventors: Timothy C. Dunn, Yalia Jayalakshmi, Ronald T. Kurnik, Matthew J. Lesho, Jonathan James Oliver, Russell O. Potts, Janet A. Tamada, Steven Richard Waterhouse, Charles W. Wei
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Publication number: 20080262334Abstract: The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.Type: ApplicationFiled: June 30, 2008Publication date: October 23, 2008Applicant: Animas Technologies, LLC.Inventors: Timothy C. Dunn, Yalia Jayalakshmi, Ronald T. Kurnik, Matthew J. Lesho, Jonathan James Oliver, Russell O. Potts, Janet A. Tamada, Steven Richard Waterhouse, Charles W. Wei
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Patent number: 7405055Abstract: The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.Type: GrantFiled: July 24, 2003Date of Patent: July 29, 2008Assignee: Animas Technologies LLCInventors: Timothy C. Dunn, Yalia Jayalakshmi, Ronald T. Kurnik, Matthew J. Lesho, Jonathan James Oliver, Russell O. Potts, Janet A. Tamada, Steven Richard Waterhouse, Charles W. Wei
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Patent number: 7228163Abstract: Methods of frequently monitoring glucose amounts and/or concentrations in a subject who is at risk for hypoglycemia, hyperglycemia, and/or glucose level fluctuations that put the subject at risk are provided. Also provided are methods of monitoring the effects of one or more pharmaceutical compositions on the levels of glucose in a subject.Type: GrantFiled: November 5, 2004Date of Patent: June 5, 2007Assignee: Animas Technologies, LLCInventor: Neil Ackerman
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Patent number: 7189341Abstract: The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, as well as methods of making, and methods of using such compositions and electrodes. An exemplary ink material comprises a metal catalyst (e.g., platinum black and/or platinum-on-carbon), graphite as a conducting material, a polymer binding material, and an organic solvent. In one aspect, the polymer binding material comprises a polymer binder blend comprising first and second polymers, wherein the first polymer has a glass transition temperature higher than the second polymer. In a second aspect, the polymer binding material comprises a hydrophilic acrylic polymer, copolymer, or terpolymer. The conductive polymer compositions of the present invention may be used, for example, to make electrochemical sensors. Such sensors may be used, for example, in a variety of devices to monitor analyte amount or concentrations in subjects.Type: GrantFiled: October 24, 2003Date of Patent: March 13, 2007Assignee: Animas Technologies, LLCInventors: Huawen Li, Michael J. Tierney
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Patent number: 7183068Abstract: This invention relates to methods for reducing the presence of a compound in an ionically conductive material, e.g., for use in iontophoretic devices, wherein the presence of the compound interferes with detecting a selected analyte. Removal of the compound can typically take place either during or after the manufacture of the ionically conductive material or an assembly comprising this material. Also disclosed are methods for generating selectively permeable barriers on the reactive faces of electrodes. Further, this invention relates to hydrogels comprising one or more biocides, as well as assemblies containing such hydrogels.Type: GrantFiled: February 17, 2005Date of Patent: February 27, 2007Assignee: Animas Technologies, LLCInventors: Kim K. Burson, Michelle Van Wyhe, Jeffrey Pudlo, Michael Reidy, Pravin Soni, Christopher Uhegbu, Prema Vijayakumar
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Patent number: 7174199Abstract: Methods and devices are provided for measuring the concentration of target chemical analytes present in a biological system. Device configuration and/or measurement techniques are employed in order to reduce the effect of interfering species on sensor sensitivity. One important application of the invention involves a method and device for monitoring blood glucose values.Type: GrantFiled: November 5, 2004Date of Patent: February 6, 2007Assignee: Animas Technologies, LLCInventors: Bret Berner, Chia-Ming Chiang, Michael D. Garrison, Janan Jona, Russell O. Potts, Janet A. Tamada, Michael J. Tierney
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Patent number: 7163511Abstract: Devices and methods are provided for frequently measuring the concentration of an analyte present in a biological system. A monitoring system having at least two components is employed in order to allow separation of data collection from data processing and display. Such separation allows greater flexibility and convenience for the user.Type: GrantFiled: January 29, 2003Date of Patent: January 16, 2007Assignee: Animas Technologies, LLCInventors: Thomas E. Conn, Russell Ford, Russell O. Potts, Pravin L. Soni, Janet A. Tamada, Michael J. Tierney
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Patent number: 7150975Abstract: The present invention relates to compositions for use in analyte monitoring devices. These compositions are useful to increase the flux of analyte across skin, tissue or mucosal surfaces. The compositions include hydrogels and collection reservoir systems comprising ionically conductive materials. The present invention also includes methods of making/manufacturing hydrogels or collection reservoir systems, collection assemblies comprising the hydrogels, electrode assemblies in combination with the hydrogels or collection reservoir systems, and methods of using the same.Type: GrantFiled: August 18, 2003Date of Patent: December 19, 2006Assignee: Animas Technologies, LLCInventors: Janet A. Tamada, Michael J. Tierney, Stephen C. Williams
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Patent number: 7024236Abstract: The present invention relates to methods of formulating analyte data databases, the databases themselves, and methods of manipulating the same. In one aspect the present invention includes the formulation of analyte data points, derived data, and data attributes databases comprising data points collected using an analyte monitoring device capable of frequent monitoring of analyte concentrations or amounts. Such data points may comprise acquired data (e.g., values corresponding to analyte concentrations or amounts as measured by said analyte monitoring device). These data points are then associated with one or more relevant data attributes. The resulting databases may be manipulated to determine relationships among the components of the database.Type: GrantFiled: April 8, 2004Date of Patent: April 4, 2006Assignee: Animas Technologies LLCInventors: Russell Ford, Matthew J. Lesho, Russell O. Potts, Michael J. Tierney, Charles W. Wei
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Patent number: 7018568Abstract: The invention is directed to conductive polymer compositions, catalytic ink compositions (e.g., for use in screen-printing), electrodes produced by deposition of an ink composition, methods of making, and methods of using thereof. An exemplary ink material comprises platinum black and/or platinum-on-carbon as the catalyst, graphite as a conducting material, a polymer binding material, and an organic solvent. The polymer binding material is typically a copolymer of hydrophilic and hydrophobic monomers. The conductive polymer compositions of the present invention can be used, for example, to make electrochemical sensors. Such sensors can be used in a variety of analyte monitoring devices to monitor analyte amount or concentrations in subjects, for example, glucose monitoring devices to monitor glucose levels in subjects with diabetes.Type: GrantFiled: December 19, 2002Date of Patent: March 28, 2006Assignee: Animas Technologies LLCInventor: Michael J. Tierney
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Patent number: 7011630Abstract: The present invention relates to methods to increase the number of analyte-related signals used to provide analyte measurement values, e.g., when two or more analyte-related signals are used to obtain a single analyte measurement value a “rolling” value based on the two or more signals can be employed. In another aspect, interpolation and/or extrapolation methods are used to estimate unusable, missing or error-associated analyte-related signals. Further, interpolation and extrapolation of values are employed in another aspect of the invention that reduces the incident of failed calibrations. Further, the invention relates to methods, which employ gradients and/or predictive algorithms, to provide an alert related to analyte values exceeding predetermined thresholds.Type: GrantFiled: June 21, 2002Date of Patent: March 14, 2006Assignee: Animas Technologies, LLCInventors: Shashi P. Desai, Timothy C. Dunn, Matthew J. Lesho, Russell O. Potts, Janet A. Tamada, Charles W. Wei
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Patent number: 6999810Abstract: An automated system for continual transdermal extraction of analytes present in a biological system is provided. The system can be used for detecting and/or measuring the concentration of the analyte using an electrochemical biosensor detection means. The system optionally uses reverse iontophoresis to carry out the continual transdermal extraction of the analytes.Type: GrantFiled: September 8, 2004Date of Patent: February 14, 2006Assignee: Animas Technologies LLCInventors: Bret Berner, Lynn Kim, Norman A. Parris, Russell O. Potts, Janet Tamada, Michael J. Tierney