Patents Assigned to ANIMATUS BIOSCIENCES, LLC
  • Enhanced cardiomyocyte regeneration
    Patent number: 11179479
    Abstract: Compositions and methods for promoting adult mammalian cardiomyocytes processes and systems for enhancing cardiomyocyte regeneration are described. The invention relates to locally administering a therapeutic agent containing a modified messenger RNA for expressing a mutated serum response factor polypeptide and a modified messenger RNA for expressing a mutated YAP polypeptide into diseased heart muscle to promote cardiomyocyte proliferation and cardiac regeneration.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: November 23, 2021
    Assignee: ANIMATUS BIOSCIENCES, LLC
    Inventors: Robert Schwartz, Dinakar Iyer, Siyu Xiao