Abstract: Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.
Type:
Grant
Filed:
August 9, 2004
Date of Patent:
December 25, 2007
Assignee:
AnorMED
Inventors:
Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria Rosaria Di Fluri
Abstract: Novel compounds that are useful for targeting chemokine receptors are disclosed. These compounds are complex tertiary amines.
Type:
Grant
Filed:
June 1, 2004
Date of Patent:
August 1, 2006
Assignee:
AnorMED
Inventors:
Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R. Wilson, Jason Crawford, Ernest J. McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria Rosaria Di Fluri
Abstract: Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.
Type:
Application
Filed:
August 9, 2004
Publication date:
February 3, 2005
Applicant:
AnorMED
Inventors:
Gary Bridger, Renato Skerlj, Al Kaller, Curtis Harwig, David Bogucki, Trevor Wilson, Jason Crawford, Ernest McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Smith, Maria Di Fluri
Abstract: The present invention is drawn to novel antiviral compounds, pharmaceutical compositions and their use. More specifically this invention is drawn to derivatives of monocyclic polyamines which have activity in standard tests against HIV- or FIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors that mediate a number of mammalian embryonic developmental processes.
Type:
Grant
Filed:
December 15, 2000
Date of Patent:
December 23, 2003
Assignee:
Anormed
Inventors:
Gary James Bridger, Eva Maria Boehringer, Zhongren Wang, Dominique Schols, Renato Tony Skerlj, David Earl Bogucki