Patents Assigned to Antares Pharma, Inc.
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Publication number: 20230109835Abstract: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.Type: ApplicationFiled: December 13, 2022Publication date: April 13, 2023Applicant: Antares Pharma, Inc.Inventors: Thomas E. Kramer, Peter L. Sadowski
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Publication number: 20230104341Abstract: Injection systems comprising a powered injector and one or more hazardous agents are disclosed.Type: ApplicationFiled: October 5, 2022Publication date: April 6, 2023Applicant: Antares Pharma, Inc.Inventors: Paul K. Wotton, Peter L. Sadowski, John W. Hayes
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Publication number: 20230099165Abstract: Aqueous hydrocortisone sodium phosphate and monothioglycerol formulations are disclosed.Type: ApplicationFiled: November 18, 2022Publication date: March 30, 2023Applicant: ANTARES PHARMA, INC.Inventors: Xiaoming CHEN, Shaowei ONG
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Patent number: 11602597Abstract: A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. The housing includes a retractable guard and an interference component, e.g., a lock ring, adjacent to the retractable guard that interferes with the movement of the retractable guard. An energy source is configured for biasing the plunger to produce an injecting pressure to jet inject the medicament from the fluid chamber through the needle to an injection site.Type: GrantFiled: October 2, 2019Date of Patent: March 14, 2023Assignee: ANTARES PHARMA, INC.Inventors: James W. Lannan, Julius C. Sund
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Patent number: 11547808Abstract: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.Type: GrantFiled: June 22, 2020Date of Patent: January 10, 2023Assignee: Antares Pharma, Inc.Inventors: Thomas E. Kramer, Peter L. Sadowski
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Publication number: 20230001093Abstract: An injector for injecting a medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, arid a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.Type: ApplicationFiled: September 9, 2022Publication date: January 5, 2023Applicant: Antares Pharma, Inc.Inventors: Paul R. LESCH, Matthew H. RUST, Thomas E. KRAMER
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Publication number: 20220379031Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.Type: ApplicationFiled: August 11, 2022Publication date: December 1, 2022Applicant: Antares Pharma, Inc.Inventors: Thomas Kramer, Matthew H. Rust, Paul M. Goudreau, Peter A. Hoeft, Julius C. Sund, Peter L. Sadowski, Michael Travanty, Patrick Madsen
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Publication number: 20220379032Abstract: A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site.Type: ApplicationFiled: August 11, 2022Publication date: December 1, 2022Applicant: Antares Pharma, Inc.Inventor: Paul R. Lesch
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Patent number: 11497753Abstract: Injection systems comprising a powered injector and one or more hazardous agents are disclosed.Type: GrantFiled: December 16, 2019Date of Patent: November 15, 2022Assignee: Antares Pharma, Inc.Inventors: Paul K. Wotton, Peter L. Sadowski, John W. Hayes
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Patent number: 11471600Abstract: An injector for injecting a medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, and a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.Type: GrantFiled: December 13, 2019Date of Patent: October 18, 2022Assignee: Antares Pharma, Inc.Inventors: Paul R. Lesch, Matthew H. Rust, Thomas E. Kramer
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Patent number: 11446440Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.Type: GrantFiled: June 10, 2019Date of Patent: September 20, 2022Assignee: ANTARES PHARMA, INC.Inventors: Thomas Kramer, Matthew H. Rust, Paul M. Goudreau, Peter A. Hoeft, Julius C. Sund, Peter L. Sadowski, Michael Travanty, Patrick Madsen
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Patent number: 11446441Abstract: A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site.Type: GrantFiled: October 11, 2019Date of Patent: September 20, 2022Assignee: ANTARES PHARMA, INC.Inventor: Paul R. Lesch, Jr.
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Publication number: 20220203040Abstract: A dispensing mechanism for delivering a dosage of medicament including a housing having a proximal-distal axis; a plunger rod having a screw thread and configured to advance along the proximal-distal axis relative to the housing; a user-operable push button moveable along the proximal-distal axis relative to the housing; a twist driver threadably engaged with the push button such that movement of the push button towards the distal end of the housing causes rotation of the twist driver about the proximal-distal axis; and a driver engaged with the twist driver such that rotation of the twist driver causes rotation of the driver, the driver also engaged with a portion of the plunger rod such that rotation of the driver causes rotation of the plunger rod, advancing the plunger rod along the proximal-distal axis relative to the housing.Type: ApplicationFiled: March 10, 2022Publication date: June 30, 2022Applicant: Antares Pharma, Inc.Inventors: Benjamin Newton, Patrick Madsen, Matthew Rust, Janice Cox
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Publication number: 20220125713Abstract: The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted injection device.Type: ApplicationFiled: November 1, 2021Publication date: April 28, 2022Applicant: Antares Pharma, Inc.Inventors: Paul K. Wotton, Jonathan Jaffe
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Patent number: 11291773Abstract: A dispensing mechanism for delivering a dosage of medicament including a housing having a proximal-distal axis; a plunger rod having a screw thread and configured to advance along the proximal-distal axis relative to the housing; a user-operable push button moveable along the proximal-distal axis relative to the housing; a twist driver threadably engaged with the push button such that movement of the push button towards the distal end of the housing causes rotation of the twist driver about the proximal-distal axis; and a driver engaged with the twist driver such that rotation of the twist driver causes rotation of the driver, the driver also engaged with a portion of the plunger rod such that rotation of the driver causes rotation of the plunger rod, advancing the plunger rod along the proximal-distal axis relative to the housing.Type: GrantFiled: April 19, 2019Date of Patent: April 5, 2022Assignee: Antares Pharma, Inc.Inventors: Benjamin Newton, Patrick Madsen, Matthew Rust, Janice Cox
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Publication number: 20220096496Abstract: Aqueous hydrocortisone sodium phosphate and monothioglycerol formulations are disclosed.Type: ApplicationFiled: October 5, 2021Publication date: March 31, 2022Applicant: ANTARES PHARMA, INC.Inventors: Xiaoming CHEN, Shaowei ONG
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Publication number: 20220080131Abstract: An exemplary embodiment of the present disclosure can provide an injector including a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.Type: ApplicationFiled: November 29, 2021Publication date: March 17, 2022Applicant: Antares Pharma, Inc.Inventors: Thomas E. Kramer, Matthew H. Rust, Paul M. Goudreau, Peter A. Hoeft, Julius C. Sund, Peter L. Sadowski
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Publication number: 20220079955Abstract: Testosterone ester triglyceride formulations, optionally further including adducts. Methods of in-situ control of the manufacture or formation of such adducts are also described.Type: ApplicationFiled: August 18, 2021Publication date: March 17, 2022Applicant: Antares Pharma, Inc.Inventor: Shaowei Ong
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Publication number: 20220062564Abstract: An injection device, for example, an auto-injector of any type, includes a sleeve configured to hold a medicament chamber. The sleeve may be sufficiently deformable such that it functions as a shock absorbing member to distribute the force exerted on the medicament chamber during use of the injection device.Type: ApplicationFiled: October 27, 2021Publication date: March 3, 2022Applicant: Antares Pharma, Inc.Inventors: John Pierre MEHAWEJ, Michael TRAVANTY
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Patent number: 11191908Abstract: An injection device, for example, an auto-injector of any type, includes a sleeve configured to hold a medicament chamber. The sleeve may be sufficiently deformable such that it functions as a shock absorbing member to distribute the force exerted on the medicament chamber during use of the injection device.Type: GrantFiled: August 7, 2015Date of Patent: December 7, 2021Assignee: Antares Pharma, Inc.Inventors: John Pierre Mehawej, Michael Travanty