Patents Assigned to ANTERIOS, INC.
  • Publication number: 20220387299
    Abstract: The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions. Methods generally involve administering nanoparticle compositions (e.g., nanoparticle compositions comprising at least one known therapeutic agent and/or independently active biologically active agent; and/or empty nanoparticle compositions) to a subject in need thereof.
    Type: Application
    Filed: March 28, 2022
    Publication date: December 8, 2022
    Applicant: Anterios, Inc.
    Inventors: Jonathan Edelson, Timothy Kotyla, Klaus Theobald
  • Publication number: 20220175634
    Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
    Type: Application
    Filed: February 15, 2022
    Publication date: June 9, 2022
    Applicant: Anterios, Inc.
    Inventors: Jonathan Edelson, Timothy Kotyla
  • Publication number: 20210308021
    Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
    Type: Application
    Filed: November 9, 2020
    Publication date: October 7, 2021
    Applicant: Anterios, Inc.
    Inventors: Jonathan Edelson, Timothy Kotyla
  • Publication number: 20210220271
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Application
    Filed: August 28, 2020
    Publication date: July 22, 2021
    Applicant: Anterios, Inc.
    Inventor: Timothy Kotyla
  • Patent number: 10905637
    Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: February 2, 2021
    Assignee: Anterios, Inc.
    Inventors: Jonathan Edelson, Timothy Kotyla
  • Patent number: 10758485
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: September 1, 2020
    Assignee: Anterios, Inc.
    Inventor: Timothy Kotyla
  • Patent number: 10485855
    Abstract: The present invention provides methods for improving observed or determined efficacy by administration of agents to more severely diseased subjects, as contrasted with less severely diseased subjects. The present disclosure specifically demonstrates that, with respect to treatment of certain skin conditions, and particularly conditions associated with dysregulated and/or diseased skin cells, administration to more severely diseased subjects improves observed or determined efficacy.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: November 26, 2019
    Assignee: Anterios, Inc.
    Inventor: Jonathan Edelson
  • Patent number: 10285941
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: May 14, 2019
    Assignee: Anterios, Inc.
    Inventor: Timothy Kotyla
  • Patent number: 10016451
    Abstract: The present invention provides nanoparticle compositions including one or more nucleic acids. The present invention achieves delivery (particularly transdermal delivery) of such nucleic acids without the need for nucleic acid modification, or for use of chemical or mechanical abrasion or disruption of skin.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: July 10, 2018
    Assignee: Anterios, Inc.
    Inventors: Jonathan Edelson, Timothy Kotyla, Boke Zhang
  • Patent number: 9724299
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: August 8, 2017
    Assignee: Anterios, Inc.
    Inventor: Timothy Kotyla
  • Patent number: 9649266
    Abstract: The present invention provides antagonists of acetylcholine receptors for the treatment of skin conditions. The present invention achieves treatment of skin conditions without causing the severe damage to the skin associated with antagonism of nicotinic acetylcholine receptors.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: May 16, 2017
    Assignee: Anterios, Inc.
    Inventor: Jonathan Edelson
  • Patent number: 9486409
    Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
    Type: Grant
    Filed: February 22, 2014
    Date of Patent: November 8, 2016
    Assignee: Anterios, Inc.
    Inventors: Jonathan Edelson, Timothy Kotyla
  • Publication number: 20140234382
    Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
    Type: Application
    Filed: February 22, 2014
    Publication date: August 21, 2014
    Applicant: Anterios, Inc.
    Inventors: Jonathan EDELSON, Timothy KOTYLA
  • Publication number: 20140161854
    Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.
    Type: Application
    Filed: February 18, 2014
    Publication date: June 12, 2014
    Applicant: Anterios, Inc.
    Inventor: Timothy KOTYLA
  • Patent number: 8658391
    Abstract: The present invention provides methods for assessing the activity of topically administered chemodenervating agents. In some embodiments, methods for assessing the activity of topically administered chemodenervating agents involve determining the extent of inhibition of acetylcholine release near the site of administration. In some embodiments, methods for assessing activity of topically administered chemodenervating agents involve observing a reflex motion of a limb of a subject.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: February 25, 2014
    Assignee: Anterios, Inc.
    Inventor: Jonathan Edelson
  • Publication number: 20120328701
    Abstract: The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions. Methods generally involve administering nanoparticle compositions (e.g., nanoparticle compositions comprising at least one known therapeutic agent and/or independently active biologically active agent; and/or empty nanoparticle compositions) to a subject in need thereof.
    Type: Application
    Filed: January 23, 2012
    Publication date: December 27, 2012
    Applicant: ANTERIOS, INC.
    Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
  • Publication number: 20120328549
    Abstract: The present invention provides oil compositions and associated methods and reagents, particularly useful for the treatment of dermatologic conditions. In some embodiments, provided compositions are formulated for and achieve transdermal delivery, for example by topical administration.
    Type: Application
    Filed: January 23, 2012
    Publication date: December 27, 2012
    Applicant: ANTERIOS, INC.
    Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
  • Publication number: 20120328702
    Abstract: The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions associated with the epidermal and/or dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, actinic keratosis, facial wrinkles, muscle contracture, and headache. Methods generally involve administering nanoparticle compositions to the skin.
    Type: Application
    Filed: January 23, 2012
    Publication date: December 27, 2012
    Applicant: ANTERIOS, INC.
    Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
  • Publication number: 20120328525
    Abstract: The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, and/or actinic keratosis, among others. Methods generally involve administering provided compositions to the skin.
    Type: Application
    Filed: January 23, 2012
    Publication date: December 27, 2012
    Applicant: ANTERIOS, INC.
    Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
  • Publication number: 20120321571
    Abstract: The present invention provides paraben compositions and associated methods and reagents, particularly useful for the treatment of dermatologic conditions. In some embodiments, provided compositions are formulated for and achieve transdermal delivery, for example by topical administration.
    Type: Application
    Filed: January 23, 2012
    Publication date: December 20, 2012
    Applicant: ANTERIOS, INC.
    Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD