Patents Assigned to ANTERIOS, INC.
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Publication number: 20220387299Abstract: The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions. Methods generally involve administering nanoparticle compositions (e.g., nanoparticle compositions comprising at least one known therapeutic agent and/or independently active biologically active agent; and/or empty nanoparticle compositions) to a subject in need thereof.Type: ApplicationFiled: March 28, 2022Publication date: December 8, 2022Applicant: Anterios, Inc.Inventors: Jonathan Edelson, Timothy Kotyla, Klaus Theobald
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Publication number: 20220175634Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.Type: ApplicationFiled: February 15, 2022Publication date: June 9, 2022Applicant: Anterios, Inc.Inventors: Jonathan Edelson, Timothy Kotyla
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Publication number: 20210308021Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.Type: ApplicationFiled: November 9, 2020Publication date: October 7, 2021Applicant: Anterios, Inc.Inventors: Jonathan Edelson, Timothy Kotyla
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Publication number: 20210220271Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.Type: ApplicationFiled: August 28, 2020Publication date: July 22, 2021Applicant: Anterios, Inc.Inventor: Timothy Kotyla
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Patent number: 10905637Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.Type: GrantFiled: September 29, 2016Date of Patent: February 2, 2021Assignee: Anterios, Inc.Inventors: Jonathan Edelson, Timothy Kotyla
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Patent number: 10758485Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.Type: GrantFiled: April 9, 2019Date of Patent: September 1, 2020Assignee: Anterios, Inc.Inventor: Timothy Kotyla
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Patent number: 10485855Abstract: The present invention provides methods for improving observed or determined efficacy by administration of agents to more severely diseased subjects, as contrasted with less severely diseased subjects. The present disclosure specifically demonstrates that, with respect to treatment of certain skin conditions, and particularly conditions associated with dysregulated and/or diseased skin cells, administration to more severely diseased subjects improves observed or determined efficacy.Type: GrantFiled: May 1, 2015Date of Patent: November 26, 2019Assignee: Anterios, Inc.Inventor: Jonathan Edelson
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Patent number: 10285941Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.Type: GrantFiled: June 29, 2017Date of Patent: May 14, 2019Assignee: Anterios, Inc.Inventor: Timothy Kotyla
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Patent number: 10016451Abstract: The present invention provides nanoparticle compositions including one or more nucleic acids. The present invention achieves delivery (particularly transdermal delivery) of such nucleic acids without the need for nucleic acid modification, or for use of chemical or mechanical abrasion or disruption of skin.Type: GrantFiled: May 30, 2008Date of Patent: July 10, 2018Assignee: Anterios, Inc.Inventors: Jonathan Edelson, Timothy Kotyla, Boke Zhang
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Patent number: 9724299Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.Type: GrantFiled: February 18, 2014Date of Patent: August 8, 2017Assignee: Anterios, Inc.Inventor: Timothy Kotyla
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Patent number: 9649266Abstract: The present invention provides antagonists of acetylcholine receptors for the treatment of skin conditions. The present invention achieves treatment of skin conditions without causing the severe damage to the skin associated with antagonism of nicotinic acetylcholine receptors.Type: GrantFiled: May 1, 2015Date of Patent: May 16, 2017Assignee: Anterios, Inc.Inventor: Jonathan Edelson
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Patent number: 9486409Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.Type: GrantFiled: February 22, 2014Date of Patent: November 8, 2016Assignee: Anterios, Inc.Inventors: Jonathan Edelson, Timothy Kotyla
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Publication number: 20140234382Abstract: The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.Type: ApplicationFiled: February 22, 2014Publication date: August 21, 2014Applicant: Anterios, Inc.Inventors: Jonathan EDELSON, Timothy KOTYLA
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Publication number: 20140161854Abstract: The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.Type: ApplicationFiled: February 18, 2014Publication date: June 12, 2014Applicant: Anterios, Inc.Inventor: Timothy KOTYLA
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Patent number: 8658391Abstract: The present invention provides methods for assessing the activity of topically administered chemodenervating agents. In some embodiments, methods for assessing the activity of topically administered chemodenervating agents involve determining the extent of inhibition of acetylcholine release near the site of administration. In some embodiments, methods for assessing activity of topically administered chemodenervating agents involve observing a reflex motion of a limb of a subject.Type: GrantFiled: April 27, 2007Date of Patent: February 25, 2014Assignee: Anterios, Inc.Inventor: Jonathan Edelson
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Publication number: 20120328701Abstract: The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions. Methods generally involve administering nanoparticle compositions (e.g., nanoparticle compositions comprising at least one known therapeutic agent and/or independently active biologically active agent; and/or empty nanoparticle compositions) to a subject in need thereof.Type: ApplicationFiled: January 23, 2012Publication date: December 27, 2012Applicant: ANTERIOS, INC.Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
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Publication number: 20120328549Abstract: The present invention provides oil compositions and associated methods and reagents, particularly useful for the treatment of dermatologic conditions. In some embodiments, provided compositions are formulated for and achieve transdermal delivery, for example by topical administration.Type: ApplicationFiled: January 23, 2012Publication date: December 27, 2012Applicant: ANTERIOS, INC.Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
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Publication number: 20120328702Abstract: The present invention describes novel nanoparticle compositions, and systems and methods utilizing them for treating disorders and/or conditions associated with the epidermal and/or dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, actinic keratosis, facial wrinkles, muscle contracture, and headache. Methods generally involve administering nanoparticle compositions to the skin.Type: ApplicationFiled: January 23, 2012Publication date: December 27, 2012Applicant: ANTERIOS, INC.Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
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Publication number: 20120328525Abstract: The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, and/or actinic keratosis, among others. Methods generally involve administering provided compositions to the skin.Type: ApplicationFiled: January 23, 2012Publication date: December 27, 2012Applicant: ANTERIOS, INC.Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
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Publication number: 20120321571Abstract: The present invention provides paraben compositions and associated methods and reagents, particularly useful for the treatment of dermatologic conditions. In some embodiments, provided compositions are formulated for and achieve transdermal delivery, for example by topical administration.Type: ApplicationFiled: January 23, 2012Publication date: December 20, 2012Applicant: ANTERIOS, INC.Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD