Patents Assigned to ANTEROGEN CO., LTD.
  • Patent number: 11945833
    Abstract: In an embodiment, the invention is directed to prodrug compounds of L-BHDU according to the chemical structure I: Where R1 is a —(CH2)n—O—R1a group or a —(CH2)j—O—C(O)Ok—R2a group; R2 is H, a —(CH2)n—O—R1a group or a —(CH2)j—O—C(O)Ok—R2a group; R1a is independently a C6-C30 alkyl group, often a C12-C22 alkyl group, often a C14-C20 alkyl group or a C16-C18 alkyl group, often a C16 or C18 alkyl group; R2a is independently a C1-C12 alkyl group, often a C2-C6 alkyl group, a C3-C4 alkyl group, an isopropyl, t-butyl or sec-butyl group, or an isopropyl or t-butyl group; Each j is independently 1-6, 1-3, often 1 or 2; Each k is 0 or 1; Each n is independently 1-6, 1-4, 2-4 or 2 or 3; or A pharmaceutically acceptable salt, solute or polymorph thereof. Additional embodiments are directed to pharmaceutical compositions based upon the disclosed chemical compounds and methods of treating or reducing the likelihood of VZV, HSV-1 or HSV-2 infections.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: April 2, 2024
    Assignees: University of Georgia Research Foundation, Inc., Anterogen Co., Ltd.
    Inventors: Uma Sharan Singh, Chung Chu
  • Patent number: 9874574
    Abstract: The present invention relates to: a composition for detecting a marker for detecting the proliferation capacity or treatment capacity of adipose-derived stem cells cultured in a medium containing epidermal growth factor (EGF) or basic fibroblast growth factor (bFGF); and a detection method.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: January 23, 2018
    Assignees: ANTEROGEN CO. LTD., KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Kyung Sook Chung, Mi Hyung Kim
  • Publication number: 20160178648
    Abstract: The present invention relates to: a composition for detecting a marker for detecting the proliferation capacity or treatment capacity of adipose-derived stem cells cultured in a medium containing epidermal growth factor (EGF) or basic fibroblast growth factor (bFGF); and a detection method.
    Type: Application
    Filed: June 11, 2014
    Publication date: June 23, 2016
    Applicants: ANTEROGEN CO. LTD., KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Kyung Sook CHUNG, Mi Hyung KIM
  • Publication number: 20120020937
    Abstract: The present invention relates to a method for producing clinically effective quantities of human adipose tissue-derived stromal cells for treating fistulas and a composition made with the same. The method of the present invention can efficiently produce clinically effective number of adipose tissue-derived stromal cells within a short period by improving conventional standard culturing methods. The adipose stem cells composition containing the adipose tissue-derived stromal cells obtained by the method of the present invention exhibit superior multipotency and immunomodulatory activity over those of a cell composition produced by conventional methods, and thus is more suitable for treating fistulas. The cell composition of the present invention has excellent clinical usages especially since immune response is suppressed in allogenic adipose-derived stem cells.
    Type: Application
    Filed: June 9, 2009
    Publication date: January 26, 2012
    Applicant: ANTEROGEN CO., LTD.
    Inventors: Sung-Koo Lee, Mi-Hyung Kim
  • Publication number: 20080286241
    Abstract: Provided is a technology involving differentiating preadipocytes, derived from human adipose tissues, into adipocytes and transplanting the differentiated adipocytes in conjunction with a biodegradable scaffold into the body. According to the present invention, when immature adipocytes having a cell diameter of 20 to 40 ?m, obtained by differentiation of adipose tissue-derived preadipocytes into adipose tissues, are used in conjunction with a scaffold in autologous or allogeneic transplantation, maturation of adipocytes at the target transplantation site leads to a gradual increase in the volume of adipocytes. Therefore, the adipocyte-scaffold composition according to the present invention can be utilized as an effective body volume replacement and can treat various disorders due to defects of soft tissues or aesthetic defects in appearance.
    Type: Application
    Filed: April 21, 2006
    Publication date: November 20, 2008
    Applicant: ANTEROGEN CO., LTD.
    Inventors: Sung-Koo Lee, Mi-Hyung Kim, In-Ok Kim