Abstract: Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.
Type:
Grant
Filed:
December 29, 2017
Date of Patent:
February 5, 2019
Assignees:
Sanaria Inc., Antigen Discovery, Inc., The United States of America, as represented by the Secretary, Department of Health and Human Services
Inventors:
Philip Felgner, Stephen L. Hoffman, Robert Seder, Joseph J. Campo, Jr.
Abstract: Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.
Type:
Application
Filed:
December 29, 2017
Publication date:
August 16, 2018
Applicants:
Sanaria Inc., Antigen Discovery, Inc., The United States of America, as represented by the Secretary, Department of Health and Human
Inventors:
Philip FELGNER, Stephen L. HOFFMAN, Robert SEDER, Joseph J. CAMPO, JR.
Abstract: Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.
Type:
Application
Filed:
March 4, 2016
Publication date:
November 3, 2016
Applicants:
Sanaria Inc., Antigen Discovery, Inc., The United States of America, as represented by the Secretary, Department of Health and Human
Inventors:
Philip FELGNER, Stephen L. HOFFMAN, Robert SEDER, Joseph J. CAMPO, Jr.