Patents Assigned to ANTION BIOSCIENCES SA
  • ADAPTER MOLECULES TO RE-DIRECT CAR T CELLS TO AN ANTIGEN OF INTEREST
    Publication number: 20230242643
    Abstract: Chimeric antigen receptor (CAR) bridging protein are provided comprising a CAR-binding domain linked to an antigen-binding domain, which can be used to re-direct the targeting of CAR-T cells. The bridging protein may comprie an antigen-binding domain that targets any antigen of interest, such as, for example, a tumor antigen or viral antigen. Also provided are methods of using the bridging proteins in combination with CAR-T cells to treat a disease, such as, for example, a cancer or an infectious disease.
    Type: Application
    Filed: May 27, 2021
    Publication date: August 3, 2023
    Applicants: ANTION BIOSCIENCES SA, GENEVA UNIVERSITY HOSPITALS, UNIVERSITY OF GENEVA, UNIVERSITY OF ZURICH
    Inventors: Marco ALESSANDRINI, Karl-Heinz KRAUSE, Renier MYBURGH