Patents Assigned to Antioxidant Pharmaceuticals Corp.
  • Pharmaceutical preparations of glutathione and methods of administration thereof
    Patent number: 6896899
    Abstract: A method of increasing glutathione levels in mammalian cells comprising administering an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a mammal on an empty stomach. Pharmaceutical formulations including glutathione are also disclosed.
    Type: Grant
    Filed: February 25, 2002
    Date of Patent: May 24, 2005
    Assignee: Antioxidant Pharmaceuticals Corp.
    Inventors: Harry B. Demopolos, Myron L. Seligman
  • Pharmaceutical preparations of glutathione and methods of administration thereof
    Patent number: 6586404
    Abstract: A method for the administration of glutathione orally comprising the administration of a bolus of glutathione which is pharmaceutically stabilized and encapsulated. The glutathione is administered on an empty stomach. The preferred stabilizer is ascorbic acid.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: July 1, 2003
    Assignee: Antioxidant Pharmaceuticals Corp.
    Inventors: Harry B. Demopolos, Myron L. Seligman
  • Pharmaceutical preparations of glutathione and methods of administration thereof
    Patent number: 6423687
    Abstract: A method for the administration of glutathione orally comprising the administration of a bolus of glutathione which is pharmaceutically stabilized and encapsulated. The glutathione is administered on an empty stomach. The preferred stabilizer is ascorbic acid.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: July 23, 2002
    Assignee: Antioxidant Pharmaceuticals Corp.
    Inventors: Harry B. Demopolos, Myron L. Seligman
  • Pharmaceutical preparations of glutathione and methods of administration thereof
    Patent number: 6350467
    Abstract: A method of increasing glutathione levels in mammalian cells comprising administering an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a mammal on an empty stomach. Pharmaceutical formulations including glutathione are also disclosed.
    Type: Grant
    Filed: June 28, 1999
    Date of Patent: February 26, 2002
    Assignee: Antioxidant Pharmaceuticals Corp.
    Inventors: Harry B. Demopoulos, Myron L. Seligman
  • Pharmaceutical preparations of glutathione and methods of administration thereof
    Patent number: 6204248
    Abstract: A method of altering an expression of a gene product in cells or an organism, comprising orally administering glutathione in an effective amount and under such conditions to alter a redox potential in the cells. The gene expression may be sensitive to redox potential through one or more of a process of induction, transcription, translation, post-translational modification, release, and/or through a receptor mediated process. The glutathione is preferably administered as an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a mammal on an empty stomach.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: March 20, 2001
    Assignee: Antioxidant Pharmaceuticals Corp.
    Inventors: Harry B. Demopoulos, Myron L. Seligman