Abstract: Assemblies, systems, and methods for isolation of target material are provided. In various embodiments, an assembly for target material isolation includes a housing having an upper portion and a lower portion together defining an inner chamber. The inner chamber includes a semi-toroidal shape and the semi-toroidal shape defines a longitudinal axis. The assembly further includes one or more fluidic connection from the exterior of the housing to the inner chamber. An isolation material (e.g., polymer wool and/or magnetic beads) may be disposed within the inner chamber. A system includes a configured to fit at least a portion of the housing and releasably couple the assembly. Upon activation of the motor, the assembly may rotate about the longitudinal axis. An angle of the platform may be adjustable to thereby change the angle of the longitudinal axis about which the assembly rotates.
Type:
Grant
Filed:
April 6, 2021
Date of Patent:
June 27, 2023
Assignee:
AnuCell Biosystems Limited
Inventors:
John Daly, Kieran Curran, Macdara Glynn, Mark McCabe, David Merrigan, Jason Ryan, John P. Griffin, Caitriona Ryan, Martin Reddin
Abstract: Assemblies, systems, and methods for isolation of target material are provided. In various embodiments, an assembly for target material isolation includes a housing having an upper portion and a lower potion together defining an inner chamber. The inner chamber includes a semi-toroidal shape and the semi-toroidal shape defines a longitudinal axis. The assembly further includes one or more fluidic connection from the exterior of the housing to the inner chamber. An isolation material (e.g., polymer wool and/or magnetic beads) may be disposed within the inner chamber. A system includes a configured to fit at least a portion of the housing and releasably couple the assembly. Upon activation of the motor, the assembly may rotate about the longitudinal axis. An angle of the platform may be adjustable to thereby change the angle of the longitudinal axis about which the assembly rotates.
Type:
Grant
Filed:
December 6, 2019
Date of Patent:
May 11, 2021
Assignee:
AnuCell Biosystems Limited
Inventors:
John Daly, Kieran Curran, Macdara Glynn, Mark McCabe, David Merrigan, Jason Ryan, John P. Griffin, Caitriona Ryan, Martin Reddin