Abstract: Provided herein are an interleukin-2 polypeptide and a fusion protein thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
Type:
Grant
Filed:
April 27, 2021
Date of Patent:
February 13, 2024
Assignee:
Anwita Biosciences, Inc.
Inventors:
Fan Ye, Eric Liao, Ella Li, Matthew Siegel, Jianing Huang, Ziyang Zhong
Abstract: Provided herein are a fusion protein comprising first and second cytokine domains, and a half-life extension domain; and a pharmaceutical composition thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
Type:
Application
Filed:
July 2, 2023
Publication date:
November 2, 2023
Applicant:
Anwita Biosciences, Inc.
Inventors:
Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang
Abstract: Provided herein are a fusion protein comprising first and second cytokine domains, and a half-life extension domain; and a pharmaceutical composition thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
Type:
Grant
Filed:
November 19, 2020
Date of Patent:
July 4, 2023
Assignee:
Anwita Biosciences, Inc.
Inventors:
Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang
Abstract: Provided herein are a fusion protein comprising an interleukin-22 domain and an albumin binding domain, and a pharmaceutical composition thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of an inflammatory disease.
Type:
Application
Filed:
July 29, 2021
Publication date:
February 3, 2022
Applicant:
Anwita Biosciences, Inc.
Inventors:
Ziyang Zhong, Fan Ye, Jianing Huang, Matthew Siegel, Ji Wang
Abstract: Provided herein are a fusion protein comprising first and second cytokine domains, and a half-life extension domain; and a pharmaceutical composition thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
Type:
Application
Filed:
November 19, 2020
Publication date:
June 3, 2021
Applicant:
Anwita Biosciences, Inc.
Inventors:
Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang