Abstract: A process for controlled chemical depolymerization of naturally occurring linear polysaccharides, more specifically glycosaminoglycans. Depolymerized glycosaminoglycans, such as heparins which are obtained according to the process and pharmaceutical compositions which contain such depolymerized heparins. In the process, the polysaccharides are subjected to the action of atomic oxygen which, preferably, is derived from hypochlorous acid.
Type:
Grant
Filed:
November 19, 1987
Date of Patent:
December 11, 1990
Assignee:
Aorca S.A.
Inventors:
Victor B. Diaz, Ricardo H. Domanico, Fernando Fussi