Patents Assigned to Apeiron Biologicals AG
  • Modified ACE2 polypeptides
    Patent number: 9757433
    Abstract: The present invention relates to modified angiotensin converting enzyme 2 (ACE2) polypeptides and pharmaceutical and analytical uses thereof. In particular, the present invention relates to Zn2+ depleted-, Zn2+ free-, mixed metal- and metal ion substituted-ACE2 as well as methods for the manufacture of these variants and uses thereof, such as therapeutic and analytic uses of these ACE2 variants.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: September 12, 2017
    Assignee: Apeiron Biologicals AG
    Inventors: Hans Loibner, Bernhard Peball, Manfred Schuster, Stefan Stranner