Patents Assigned to Apeiron Biologics Forschungs-und Entwicklungsgesellschaft m.b.H.
  • Method for determining ACE2 activity
    Patent number: 8241864
    Abstract: Methods of determining ACE2 activity in a sample by reacting the sample with ACE2-binding units immobilized on a solid carrier and specific for a part of ACE2 not involved in the catalytic activity of ACE2. The reaction provides a signal that can be correlated with the ACE2 activity. These methods allow for ACE2 activity in complex solutions, such as bodily liquids or culture supernatants, to be quantitatively determined using the endogenous activity of the enzyme to be quantified by converting a signal-providing substrate.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: August 14, 2012
    Assignee: Apeiron Biologics Forschungs-und Entwicklungsgesellschaft m.b.H.
    Inventors: Hans Loibner, Manfred Schuster, Evelyne Janzek-Hawlat