Abstract: The present invention features the use of selected complement activation inhibitor(s) for treating an individual who has suffered a severe injury. The complement activation inhibitor acts at or above the level of C3 activation and does not significantly deplete or irreversibly inhibit complement activation. Also provided are compositions and methods for repleting and/or enhancing complement activation capacity in a subject who has suffered a traumatic injury.
Type:
Application
Filed:
March 30, 2009
Publication date:
August 4, 2011
Applicant:
APELLIS AG
Inventors:
Cedric Francois, Pascal Deschatelets, Paul Olson