Abstract: The invention relates to fusion proteins comprising an antigen binding domain fused with a modified heat shock 70 protein. The invention further relates to methods of using the fusion proteins to induce an immune response to antigens and to treat diseases associated With antigens.
Type:
Grant
Filed:
August 5, 2019
Date of Patent:
August 8, 2023
Assignees:
Aperisys, Inc., The General Hospital Corporation
Inventors:
Timothy Brauns, Mark C. Poznansky, Jeffrey A. Gelfand, Huabiao Chen, Stephen J. McCormack