Patents Assigned to Apex Biotechnology Corp.
  • Publication number: 20230031475
    Abstract: An electrochemical detection system is configured to detect a sample. The electrochemical detection system includes an electrochemical test strip and a measuring instrument. The electrochemical test strip includes a main body and at least one electrode group. The measuring instrument is electrically connected to the at least one electrode group. The measuring instrument is adapted to determine whether a flow field condition of the sample is normal via the at least one electrode group.
    Type: Application
    Filed: November 30, 2021
    Publication date: February 2, 2023
    Applicant: APEX BIOTECHNOLOGY CORP.
    Inventors: Chen-Yu Yang, Yu-Han Tseng
  • Patent number: 11298696
    Abstract: The present disclosure provides a reaction cassette for biochemical test. The reaction cassette includes a structural wall, a first flow guiding member and an obstacle member. The structural wall defines a reaction region and a channel region, wherein the reaction region is connected to the channel region. The first flow guiding member is disposed in the channel region, and a first angle between the structural wall and the first flow guiding member ranges between 0 and 60 degrees. The obstacle member is disposed on the structural wall, and a second angle between the obstacle member and the structural wall is greater than 90 degrees. The present disclosure further provides an assay device including said reaction assay for biochemical test.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: April 12, 2022
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventors: Sz Hau Chen, Ming Chang Hsu, Yu-Ju Lu, Chia-Jung Wang, Jui-Pin Hrian
  • Patent number: 10113986
    Abstract: Provided is an electrochemical test strip, including: a sampling end disposed on a wide side of the electrochemical test strip to receive a sample; a connection end disposed on another wide side of the electrochemical test strip to connect with a measuring meter; and at least one protrusion disposed on a long side of the electrochemical test strip. A strip board and method for generating the electrochemical test strip are further provided.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: October 30, 2018
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventors: Ching Yuan Shih, Meng Lun Lo, Wen Chien Jen, Mon Wen Yang
  • Patent number: 9968929
    Abstract: A reaction cassette and a biochemical assay device are disclosed. The reaction cassette for biochemical assay comprises a housing with structural walls defining a liquid mixing space for accommodating at least one mixing zone, wherein the at least one mixing zones comprises at least one blending structures for generating a vortex phenomenon in liquid, thereby improving the degree of mixture of a liquid sample and a dried reagent.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: May 15, 2018
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventors: Sz Hau Chen, Ming Chang Hsu, Ya Chun Wu, Tin En Lin
  • Publication number: 20180125400
    Abstract: A glucose measuring device and apparatus are provided. The device includes a substrate, a cover plate, an electrode assembly, and a reactive unit. The substrate has a first and second surfaces opposite to each other, and a flow channel located at the first surface. The flow channel includes a sampling region having a sample inlet, a measuring region, and a concentrating region therebwtween. The cover plate having a gas outlet is disposed on the first surface and covers the flow channel. The electrode assembly includes a first, a second and a third electrode pairs. The first electrode pair is at a boundary between the sampling and the concentrating regions. The second electrode pair is at a boundary between the concentrating and the measuring regions. The third electrode pair is located in the measuring region. The reactive unit is disposed on the third electrode pair and in the flow channel.
    Type: Application
    Filed: February 16, 2017
    Publication date: May 10, 2018
    Applicant: APEX BIOTECHNOLOGY CORP.
    Inventors: Mon-Wen Yang, Ying-Che Huang
  • Patent number: 9880128
    Abstract: The present disclosure relates to an electrode strip, a sensor strip, a system thereof and a manufacturing method thereof. The sensor strip includes a first reactive film, a second reactive film and a vent hole. The first reactive film includes a substrate, a first electrode layer and a first insulation layer. The first end of the first insulation layer is concaved to a first depth to form a first reactive area. The second reactive film includes a second electrode layer and a second insulation layer. The first end of the second insulation layer is concaved to a second depth to form a second reactive area. The vent hole penetrates the second insulation layer, the second electrode layer and the first insulation layer so as to connect the first reactive area and the second reactive area.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: January 30, 2018
    Assignee: Apex Biotechnology Corp.
    Inventors: Ying-Che Huang, Lan-Hsiang Huang, Ching-Yuan Chu
  • Patent number: 9823242
    Abstract: The present disclosure further provides a sensor strip. The sensor strip includes a substrate. The substrate includes a first surface, a second surface, a recess between the first surface and the second surface, and a third surface in the recess, wherein the third surface is hydrophobic. A first electrode set is disposed on top of the first surface, and a second electrode set is disposed on top of the second surface. A covering layer includes a covering surface, such as a hydrophilic surface, facing the substrate.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: November 21, 2017
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventors: Ting En Lin, Chong Chien Tay
  • Patent number: 9823213
    Abstract: An electrochemical test strip, measurement system and method for determining sample content in the reactive region of the electrochemical test strip are presented. The electrochemical test strip comprises an insulator substrate which includes an electrode system disposed thereon. The electrode system includes at least one pair of electrodes. A lower plate which includes a reactive region and a sampling cell is disposed on the insulator substrate. An upper plate is disposed on the lower plate, wherein the at least one pair of electrodes is designed as an electrical loop adjacent to the sampling port.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: November 21, 2017
    Assignee: Apex Biotechnology Corp.
    Inventors: Ching Yuan Chu, Chun Ming Cheng, Po Min Wang, Lee Teng Yi Wu
  • Patent number: 9719955
    Abstract: A hematocrit (HCT) measurement system and measurement method using the same are disclosed. The hematocrit (HCT) measurement system comprises a test strip and a measurement apparatus comprising: a connector transmitting an initial signal generated from a blood sample to the measurement apparatus, a capacitive reactance adjustor disposed between the test strip and the measurement apparatus, a calculation unit for calculating concentration and HCT value of the blood sample, an A/D convertor transforming the corresponding initial signal to a digital signal, and a signal processor processing the digital reacted signal and showing measured results on a display, wherein the HCT value is calculated by voltage partition to prevent the signal waveform voltage being saturated or cutoff, thereby resulting in measured signal distortion.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: August 1, 2017
    Assignee: Apex Biotechnology Corp.
    Inventors: Chu-Ming Cheng, Lee Teng Yi Wu, Ching-Yuan Chu
  • Publication number: 20170138889
    Abstract: A biological test sheet includes an insulating substrate, an electrode structure, a first insulating septum and an insulating layer. The electrode structure is disposed on the insulating substrate and has at least one top surface and at least one side surface, and the side surface is connected between at least one fringe of the top surface and the insulating substrate. The first insulating septum is disposed on the insulating substrate and partially covers the electrode structure. The first insulating septum has a notch, and the notch exposes a first segment of the electrode structure. The insulating layer covers the fringe of the top surface and the side surface at the first segment of the electrode structure.
    Type: Application
    Filed: November 7, 2016
    Publication date: May 18, 2017
    Applicant: APEX BIOTECHNOLOGY CORP.
    Inventors: Sz-Hau Chen, Ya-Chun Chang, Chia-Wen Tsai, Mon-Wen Yang
  • Patent number: 9470648
    Abstract: The present disclosure relates to an electrode strip, a sensor strip and a system thereof. The electrode strip includes a substrate, an electrode layer, an insulation layer and a cover. The electrode layer is disposed on the substrate. The electrode layer includes a first electrode set and a second electrode set. The insulation layer includes a groove, a first protrusion and a second protrusion. The first protrusion and the second protrusion divide the groove into two reactive areas such as a first reactive area and a second reactive area. The cover includes a vent-hole connecting to the groove, and the cover is disposed on the insulation layer.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: October 18, 2016
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventor: Sz Hau Chen
  • Patent number: 9068967
    Abstract: Devices and methods for measuring prothrombin time (PT) and hematocrit (HCT) by analyzing the change in reactance in a sample are presented. A diagnostic device for measuring HCT and PT of a fluid includes a relative electrode-type sensor device and a blood test card assembly including one or more pairs of electrodes, wherein alternating current (AC) provided by the sensor device is used to measure and calculate HCT and PT of blood test using the reactance analysis.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: June 30, 2015
    Assignee: Apex Biotechnology Corp.
    Inventors: Sz-Hau Chen, Yueh-Hui Lin, Ching-Yuan Chu, Chu-Ming Cheng, Guan-Ting Chen, Yi-Chen Lu, Thomas Y. S. Shen
  • Patent number: 9039877
    Abstract: The present disclosure relates to an electrode strip, a sensor strip, a system thereof and a manufacturing method thereof. The sensor strip includes a first reactive film, a second reactive film and a vent hole. The first reactive film includes a substrate, a first electrode layer and a first insulation layer. The first end of the first insulation layer is concaved to a first depth to form a first reactive area. The second reactive film includes a second electrode layer and a second insulation layer. The first end of the second insulation layer is concaved to a second depth to form a second reactive area. The vent hole penetrates the second insulation layer, the second electrode layer and the first insulation layer so as to connect the first reactive area and the second reactive area.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: May 26, 2015
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventors: Ying-Che Huang, Lan-Hsiang Huang, Ching-Yuan Chu
  • Patent number: 9005415
    Abstract: The present disclosure relates to an electrode strip, a sensor strip, a system thereof and a manufacturing method thereof. The sensor strip includes a first reactive film, a second reactive film and a vent hole. The first reactive film includes a substrate, a first electrode layer and a first insulation layer. The first end of the first insulation layer is concaved to a first depth to form a first reactive area. The second reactive film includes a second electrode layer and a second insulation layer. The first end of the second insulation layer is concaved to a second depth to form a second reactive area. The vent hole penetrates the second insulation layer, the second electrode layer and the first insulation layer so as to connect the first reactive area and the second reactive area.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: April 14, 2015
    Assignee: Apex Biotechnology Corp.
    Inventors: Ying-Che Huang, Lan-Hsiang Huang, Ching-Yuan Chu
  • Patent number: 9000770
    Abstract: Electrochemical blood test strips and diagnosis systems are presented. An electrochemical blood test strip for measuring HCT% and prothrombin time includes an electrode plate having electrode circuit patterns on an insulator substrate; a separation plate disposed on the electrode plate defining a blood sample region, a channel and three reaction regions; and a cover plate disposed on the separation plate having a blood sample inlet and vents. In measuring, one of the three reaction regions is used for detecting hemoglobin and hematocrit and the other two reaction regions are biochemical reaction regions and used for detecting prothrombin time.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: April 7, 2015
    Assignee: Apex Biotechnology Corp.
    Inventors: Sz-Hau Chen, Yi-Chen Lu, Chun-Yi Yen
  • Publication number: 20140367261
    Abstract: Devices and methods for measuring prothrombin time (PT) and hematocrit (HCT) by analyzing the change in reactance in a sample are presented. A diagnostic device for measuring HCT and PT of a fluid includes a relative electrode-type sensor device and a blood test card assembly including one or more pairs of electrodes, wherein alternating current (AC) provided by the sensor device is used to measure and calculate HCT and PT of blood test using the reactance analysis.
    Type: Application
    Filed: July 25, 2014
    Publication date: December 18, 2014
    Applicant: Apex Biotechnology Corp.
    Inventors: Sz-Hau Chen, Yueh-Hui Lin, Ching-Yuan Chu, Chu-Ming Cheng, Guan-Ting Chen, Yi-Chen Lu, Thomas Y.S. Shen
  • Patent number: 8828322
    Abstract: Devices and methods for measuring prothrombin time (PT) and hematocrit (HCT) by analyzing the change in reactance in a sample are presented. A diagnostic device for measuring HCT and PT of a fluid includes a relative electrode-type sensor device and a blood test card assembly including one or more pairs of electrodes, wherein alternating current (AC) provided by the sensor device is used to measure and calculate HCT and PT of blood test using the reactance analysis.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: September 9, 2014
    Assignee: Apex Biotechnology Corp.
    Inventors: Sz-Hau Chen, Yueh-Hui Lin, Ching-Yuan Chu, Chu-Ming Cheng, Guan-Ting Chen, Yi-Chen Lu, Thomas Y.S. Shen
  • Publication number: 20140238854
    Abstract: The present disclosure relates to an electrode strip, a sensor strip and a system thereof. The electrode strip includes a substrate, an electrode layer, an insulation layer and a cover. The electrode layer is disposed on the substrate. The electrode layer includes a first electrode set and a second electrode set. The insulation layer includes a groove, a first protrusion and a second protrusion. The first protrusion and the second protrusion divide the groove into two reactive areas such as a first reactive area and a second reactive area. The cover includes a vent-hole connecting to the groove, and the cover is disposed on the insulation layer.
    Type: Application
    Filed: December 20, 2013
    Publication date: August 28, 2014
    Applicant: APEX BIOTECHNOLOGY CORP.
    Inventor: SZ HAU CHEN
  • Patent number: 8802036
    Abstract: A reaction cassette for biochemical assay, a biochemical assay device including a first space configured to accommodate liquid, having a first opening and rounding edges, a direction of the first opening being directed upward. A second space includes a second opening, a direction of the second opening being perpendicular to the direction of the first opening, wherein the first space and the second space are disposed such that when the reaction cassette is rotated allowing the liquid to drain into the second space. A third space is located below the first space and having a third opening, a direction of the third opening being upward such that when the reaction cassette is reversibly rotated allowing the liquid to drain into the third space, wherein an array of bumps is disposed in the third space to create turbulence of the liquid. An inner partition wall, connected with the second opening and the third opening, acts as a liquid flow channel between the second space and the third space.
    Type: Grant
    Filed: November 4, 2012
    Date of Patent: August 12, 2014
    Assignee: Apex Biotechnology Corp.
    Inventors: Sz-Hau Chen, Yueh-Hui Lin, Chun-Ju Chen
  • Patent number: D790376
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: June 27, 2017
    Assignee: APEX BIOTECHNOLOGY CORP.
    Inventors: Chia-Yi Peng, Ming-Chang Hsu