Patents Assigned to Apibio
  • Publication number: 20060189555
    Abstract: The invention relates to novel pyrrole derivatives of the formula (I) which make it possible to immobilize and address oligonucleotides by electropolymerization. Said invention also relates to thus produced electroactive polymers and to methods for using them for detecting, identifying and dosing analytes in a sampe. (I) wherein R1 is one type of oligonucleotide, Y is S or O, X is a spacer arm selected from —(CH2)—O—, —(CH2)<SB>P</SB>O—[(CH2)2—O]q—, —(CH2)r; —CO—NR—(CH2)r-0-, —CH2r—NCH3—(CH2)r—O—, —CH2)rCO—NR?—[CH2)2—O]s—, —(CH2)rNCH3[(CH2)2—O]<SB>S</SB>—, R? is H or CH3, n is an integer number ranging from 1 to 5, p is an integer number ranging from 1 to 2, q is an integer number ranging from 1 to 4, r is an integer number ranging from 1 to 3, r? is an integer number ranging from 1 to 3, s is an integer number ranging from 1 to 3, n, p, q, r, r? and s are identical or different, a pyrrole cycle is substituted in a position 2, 3, 4 or 5.
    Type: Application
    Filed: December 16, 2003
    Publication date: August 24, 2006
    Applicants: APIBIO, BIOMERIEUX
    Inventors: Bernard Mandrand, Daniela Zsoldos, Alain Laurent, Carole Chaix, Nicolas Spinelli
  • Publication number: 20060049046
    Abstract: The invention concerns a sensor (1), in particular a biosensor, comprising an electrically or electronically insulating support (2), including at least one active surface (20), a plurality of electrically or electronically conductive electrodes (31,32), arranged on the active surface (2a) of the support in a predetermined operative arrangement, exposed, that is said electrodes can be jointly placed in contact with a common external medium, for example a liquid medium; a plurality of electric terminals (4) respectively corresponding to said electrodes (4), arranged on the active surface (2a, 2b) of the support, exposed, that is said terminals can be electrically or electronically connected outside, independently of one another; a plurality of electrically or electronically conductive strips (5), extending along one (2a) and/or the other (2d) of the support surfaces, connecting the plurality of electrodes (31,32) respectively to the plurality of terminals (4); an electrically or electronically insulating materi
    Type: Application
    Filed: July 18, 2003
    Publication date: March 9, 2006
    Applicant: APIBIO
    Inventors: Marc Cuzin, Michel Guy, Philippe Cleuziat
  • Patent number: 6852552
    Abstract: A process for selective deposition of material on electrodes of chips made from a single substrate. The process includes forming a plurality of chips on the same substrate. Each chip includes a plurality of electrodes, address pads, and an address area containing the programmed address of the chip. The address areas are connected to the address pads and capable of recognizing the address of the chip to activate the chip. The process also includes establishing electrical connections to connect the address pads and the plurality of electrodes on each chip for the activation of the chips and polarization of the electrodes. Further, the process includes addressing the chips and electrodes on which a first material is to be deposited, and simultaneously depositing the first material on the addressed electrodes of the activated chips. The addressing and deposition steps are repeated as many times as necessary to make material depositions on the other electrodes.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: February 8, 2005
    Assignees: Commissariat a l'Energie Atomique, Apibio
    Inventors: Claudine Jaffard, Marc Belleville, Catherine Bour