Patents Assigned to APICORE US LLC
  • Process of making regadenoson and novel polymorph thereof
    Patent number: 10442832
    Abstract: Novel processes for making the N-pyrrazole substituted 2-adenosine derivative regadenoson and a novel polymorph thereof. The novel polymorph of regadenoson designated form H and drug substances and pharmaceutical compositions including the novel polymorph H are disclosed.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: October 15, 2019
    Assignee: APICORE US LLC
    Inventors: Ravishanker Kovi, Ashish Naik, Piyush Fadadu, Jayaraman Kannapan
  • PROCESS FOR PREPARING HEPARINOIDS AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF
    Publication number: 20140336369
    Abstract: Processes are disclosed for the synthesis of the Factor Xa anticoagulant fondaparinux and related compounds. Protected pentasaccharide intermediates and efficient and scalable processes for the industrial scale production of fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions are provided.
    Type: Application
    Filed: July 23, 2014
    Publication date: November 13, 2014
    Applicant: APICORE US LLC
    Inventors: Ravishanker Kovi, Ashish Naik, Brijesh Patel, Muralikrishna Madala