Patents Assigned to Apocell, Inc
  • c-KIT Phosphorylation in Cancer
    Publication number: 20100143935
    Abstract: An antibody is disclosed for the detection of phosphorylated c-KIT. A method of diagnosing and monitoring cancers responsive to treatment using an anti-phospho-c-KIT antibody are also disclosed. A diagnostic kit is also provided for the detection and monitoring of cancers responsive to tyrosine phosphorylation inhibitor treatment.
    Type: Application
    Filed: December 3, 2007
    Publication date: June 10, 2010
    Applicant: Apocell, Inc.
    Inventor: Darren W. Davis
  • Evaluating RTK Target Drugs
    Publication number: 20100112617
    Abstract: Methods of evaluating receptor tyrosine kinase drug efficacy are demonstrated. The methods generally relate to evaluation methods using phospho-RTK over total RTK ratio (pRTK/tRTK). An algorithm is provided that allows the user to combine the pRTK/tRTK ratios from several kinase together with other kinds of measurements to obtain a PDX value that is indicative of drug efficacy.
    Type: Application
    Filed: March 7, 2008
    Publication date: May 6, 2010
    Applicant: Apocell, Inc
    Inventor: Darren W. Davis