Patents Assigned to Apollon, Inc.
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Patent number: 12287291Abstract: A compact Raman spectroscopic analysis device includes a housing that forms an internal accommodation space therein, a light source unit that is disposed within the housing and irradiates light onto a subject, a light receiving unit that is disposed within the housing and receives light reflected or scattered from the subject to obtain a Raman spectrum, and a processor that is disposed within the housing and configured to analyze biological material of the subject based on a peak area value of a Raman spectrum range corresponding to the biological material. The light receiving unit includes a diffraction grating that reflects the reflected or scattered light, a slit through which the reflected light passes, and a light detector.Type: GrantFiled: October 29, 2024Date of Patent: April 29, 2025Assignee: Apollon Inc.Inventors: Miyeon Jue, Young Kyu Kim, Aram Hong
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Patent number: 11986295Abstract: Disclosed is a blood glucose level measuring apparatus utilizing a Raman spectrum includes a housing defining an interior accommodation space, a light source part disposed in the housing, and that irradiates light to a subject, a light receiving part disposed in the housing, and that receives the reflected and scattered light from the subject and acquires a Raman spectrum, and a processor disposed in the housing, and that extracts information on glucose, proteins, and fats of the subject by utilizing an area of a peak included in the Raman spectrum. The processor performs a calibration by controlling the light source part and the light receiving part when the blood glucose level measuring apparatus starts to be driven or is mounted on a body of a user.Type: GrantFiled: August 24, 2023Date of Patent: May 21, 2024Assignee: Apollon Inc.Inventors: Miyeon Jue, Young Kyu Kim, Aram Hong
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Publication number: 20020161218Abstract: Nucleic acid molecule that comprise an incomplete hepatitis C viral genome including specifically disclosed DNA sequences are disclosed. Pharmaceutical compositions that contain nucleic acid molecules comprising an incomplete hepatitis C viral genome including a nucleotide sequence encoding a complete hepatitis C core protein operably linked to regulatory elements functional in human cells are disclosed.Type: ApplicationFiled: May 1, 2001Publication date: October 31, 2002Applicant: Apollon, Inc.Inventors: Catherine J. Pachuk, Jack Wands, Takaji Wakita, Vincent R. Zurawski, Leslie R. Coney
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Patent number: 6235888Abstract: Nucleic acid molecule that comprise an incomplete hepatitis C viral genome including specifically disclosed DNA sequences are disclosed. Pharmaceutical compositions that contain nucleic acid molecules comprising an incomplete hepatitis C viral genome including a nucleotide sequence encoding a complete hepatitis C core protein operably linked to regulatory elements functional in human cells are disclosed. Methods of immunizing individuals susceptible to or infected by hepatitis C virus comprising the step of administering such pharmaceutical compositions are disclosed.Type: GrantFiled: June 5, 1997Date of Patent: May 22, 2001Assignees: The General Hospital Corporation, Apollon, Inc.Inventors: Catherine J. Pachuk, Jack Wands, Takaji Wakita, Vincent R. Zurawski, Jr., Leslie R. Coney
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Patent number: 5962428Abstract: Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a genetic vaccine facilitator and administering to the cells a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produces a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.Type: GrantFiled: September 16, 1996Date of Patent: October 5, 1999Assignees: Apollon, Inc., The Trustees Of The University of PennsylvaniaInventors: Richard A. Carrano, Bin Wang, David B. Weiner
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Patent number: 5851804Abstract: Chimeric kanamycin resistance genes are disclosed. The chimeric genes comprise a nucleotide sequence that encodes ANT(4')-IA enzyme operably linked to a heterologous promoter and a heterologous termination sequence. Plasmids that comprise the chimeric kanamycin resistance gene are disclosed. Bacterial cells that comprise the chimeric gene on a plasmid or integrated into the bacterial genome are disclosed. Methods of producing plasmids are disclosed. Pharmaceutical compositions comprising plasmids that include the chimeric genes are disclosed. Methods of enhancing growth of a bacterial cells are disclosed. Plasmid which comprise the chimeric kanamycin resistance gene and the sequences from herpes simplex virus gene HSVgD.sub.2 or human immunodeficiency virus are disclosed.Type: GrantFiled: May 6, 1996Date of Patent: December 22, 1998Assignee: Apollon, Inc.Inventors: Linda Anne Snyder, C. Satishchandran
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Patent number: 5739118Abstract: Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a genetic vaccine facilitator and administering to the cells, a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produce a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.Type: GrantFiled: April 1, 1994Date of Patent: April 14, 1998Assignees: Apollon, Inc., The Trustees of the University of PennsylvaniaInventors: Richard A. Carrano, Bin Wang, David B. Weiner