Patents Assigned to Apollonian Biosystems Limited
  • Methods to produce mast cell culture
    Patent number: 9394519
    Abstract: The present invention relates to mast cell cultures that are derived from hematopoietic progenitors and the use thereof. The invention describes a method for generating in-vitro cultures of human mast cells with functional phenotype of connective tissue-type mast cells. By monitoring the levels of chemokines released into the medium, such mast cell cultures can be used as a cell-based assay to assess regulation of mast cell functions and pharmacological activities of tryptase inhibitors.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: July 19, 2016
    Assignee: Apollonian Biosystems Limited
    Inventors: See-Ying Tam, Yee San Issan Tam, Hang Yung Alaster Lau
  • Mast Cell Culture and Methods to Produce the Culture
    Publication number: 20140212971
    Abstract: The present invention relates to mast cell cultures that are derived from hematopoietic progenitors and the use thereof. The invention describes a method for generating in-vitro cultures of human mast cells with functional phenotype of connective tissue-type mast cells. By monitoring the levels of chemokines released into the medium, such mast cell cultures can be used as a cell-based assay to assess regulation of mast cell functions and pharmacological activities of tryptase inhibitors.
    Type: Application
    Filed: April 3, 2014
    Publication date: July 31, 2014
    Applicant: Apollonian Biosystems Limited
    Inventors: See-Ying TAM, Yee San Issan TAM, Hang Yung Alaster LAU