Patents Assigned to Apotech Research and Development Ltd.
  • Publication number: 20090053252
    Abstract: The invention relates to oligomers of a dimer, trimer, quatromer or pentamer of recombinant fusion proteins. Said oligomers are characterized in that the recombinant fusion proteins have at least one component A and at least one component B, whereby component A contains a protein or a protein segment with a biological function, in particular with a ligand function for antibodies, for soluble or membranous signal molecules, for receptors or an antibody, or an antibody segment, and component B contains a protein or a protein segment which dimerizes or oligomerizes the dimer, trimer, quatromer or pentamer of the recombinant fusion protein, without the action of third-party molecules. The invention also relates to the use of dimers or oligomers of this type for producing a medicament, to the fusion proteins which cluster in dimers or oligomers and to their DNA sequence and expression vectors or host cells comprising this DNA sequence.
    Type: Application
    Filed: June 2, 2008
    Publication date: February 26, 2009
    Applicant: Apotech Research and Development Ltd.
    Inventors: Jurg Tschopp, Pascal Schneider, Nils Holler
  • Patent number: 7385032
    Abstract: The invention relates to oligomers of a dimer, trimer, quatromer or pentamer of recombinant fusion proteins. The oligomers are characterized in that the recombinant fusion proteins have at least one component A and at least one component B, whereby component A contains a protein or a protein segment with a biological function, in particular with a ligand function for antibodies, for soluble or membranous signal molecules, for receptors or an antibody, or an antibody segment, and component B contains a protein or a protein segment which dimerizes or oligomerizes the dimer, trimer, quatromer or pentamer of the recombinant fusion protein, without the action of third-party molecules. The invention also relates to the use of dimers or oligomers of this type for producing a medicament, to the fusion proteins which cluster in dimers or oligomers and to their DNA sequence and expression vectors or host cells comprising this DNA sequence.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: June 10, 2008
    Assignee: Apotech Research and Development Ltd.
    Inventors: Jürg Tschopp, Pascal Schneider, Nils Holler
  • Publication number: 20020086832
    Abstract: The use of inhibitors of cysteine aspartate proteins (caspases) for treating diseases or disorders caused by a hyperproliferation of peripheral blood lymphocytes is disclosed. The use of caspase inhibitors for suppressing the immune system is also disclosed.
    Type: Application
    Filed: October 9, 2001
    Publication date: July 4, 2002
    Applicant: APOTECH RESEARCH AND DEVELOPMENT LTD.
    Inventors: Ralph C. Budd, Jurg Tschopp, Takao Kataoka