Patents Assigned to Apotex USA Inc.
  • Stable solid formulation of enalapril salt and process for preparation thereof
    Patent number: 5573780
    Abstract: There is disclosed a stable pharmaceutical solid composition comprising enalapril as the sodium salt, which is made by the steps of:i) mixing enalapril maleate with a carrier, an alkaline sodium compound, and waterii) drying the wet mass, and;iii) further processing the resultant dried mass into tablets.When the water is added in the aforesaid process, an acid-base reaction occurs which converts the enalapril maleate into the more stable enalapril sodium salt.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: November 12, 1996
    Assignee: Apotex USA Inc.
    Inventor: Bernard C. Sherman