Abstract: The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The present disclosure also provides strategies for using said compounds, compositions and microspheres in the treatment of nephrolithiasis or kidney stone disease, and methods of manufacturing and preparing said compounds and compositions.
Type:
Grant
Filed:
August 2, 2022
Date of Patent:
February 20, 2024
Assignee:
APPLAUD MEDICAL, INC.
Inventors:
Daniel J. Laser, Alice Luong, Robert G. Miotke
Abstract: The present invention is directed to a novel target detecting device comprising an excitation transducer generating a low frequency pulses of weakly focused ultrasonic energy and a sensing transducer. The present invention also includes a method of aligning a treatment transducer to a target by mapping the target in situ by sending a low frequency ultrasound signal and receiving reflected signals from the target. These inventions provide a simpler way of determining the location of a target and aligning a treatment transducer without the need to generate and interpret an image and then translate the image back onto the target.
Abstract: The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The present disclosure also provides strategies for using said compounds, compositions and microspheres in the treatment of nephrolithiasis or kidney stone disease, and methods of manufacturing and preparing said compounds and compositions.
Type:
Grant
Filed:
August 2, 2022
Date of Patent:
December 19, 2023
Assignee:
Applaud Medical, Inc.
Inventors:
Daniel J. Laser, Alice Luong, Robert G. Miotke
Abstract: The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The present disclosure also provides strategies for using said compounds, compositions and microspheres in the treatment of nephrolithiasis or kidney stone disease, and methods of manufacturing and preparing said compounds and compositions.
Type:
Grant
Filed:
January 22, 2021
Date of Patent:
October 11, 2022
Assignee:
Applaud Medical, Inc.
Inventors:
Daniel J. Laser, Alice Luong, Robert G. Miotke
Abstract: The present invention is directed to a novel target detecting device comprising an excitation transducer generating a low frequency pulses of weakly focused ultrasonic energy and a sensing transducer. The present invention also includes a method of aligning a treatment transducer to a target by mapping the target in situ by sending a low frequency ultrasound signal and receiving reflected signals from the target. These inventions provide a simpler way of determining the location of a target and aligning a treatment transducer without the need to generate and interpret an image and then translate the image back onto the target.
Abstract: The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The present disclosure also provides strategies for using said compounds, compositions and microspheres in the treatment of nephrolithiasis or kidney stone disease, and methods of manufacturing and preparing said compounds and compositions.
Type:
Grant
Filed:
January 28, 2020
Date of Patent:
March 23, 2021
Assignee:
Applaud Medical, Inc.
Inventors:
Daniel J. Laser, Alice Luong, Robert G. Miotke