Abstract: A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.
Type:
Grant
Filed:
October 4, 2022
Date of Patent:
September 19, 2023
Assignee:
APPLIED COGNITION, INC.
Inventors:
Paul Dagum, Gregory T. A. Kovacs, Laurent B. Giovangrandi, Carl J. Weber, Joerg C. Student, Nathan Whipple, Jonathan I. Kaplan
Abstract: A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.
Type:
Grant
Filed:
April 5, 2022
Date of Patent:
October 25, 2022
Assignee:
APPLIED COGNITION, INC.
Inventors:
Paul Dagum, Gregory T. A. Kovacs, Laurent B. Giovangrandi, Carl J. Weber, Joerg C. Student, Nathan Whipple, Jonathan I. Kaplan