Patents Assigned to Applied Microbiology, Inc.
  • Pharmaceutical compositions against gastric disorders
    Patent number: 5559096
    Abstract: The invention concerns pharmaceutical compositions for use in the treatment of gastric disorders associated with Helicobacter pylori comprising a bacteriocin antimicrobial agent optionally coadministered with a release-delaying substance.
    Type: Grant
    Filed: December 14, 1993
    Date of Patent: September 24, 1996
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter J. Edwards, Kim Morwood
  • Pharmaceutical bacteriocin compositions and methods for using the same
    Patent number: 5334582
    Abstract: Compositions comprising lanthionine-containing bacteriocins such as nisin in combination with a chelator act as bactericides in low pH environments. In a preferred embodiment pharmaceutical preparations containing the compositions are used for the control of bacteria responsible for disorders of the gastrointestinal tract.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: August 2, 1994
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter Blackburn, Steven J. Projan, Edward B. Goldberg
  • Pharmaceutical bacteriocin compositions and methods for using the same
    Patent number: 5304540
    Abstract: Compositions comprising lanthionine-containing bacteriocins such as nisin act as bactericides under conditions such as those found in the gastrointestinal tract. In a preferred embodiment pharmaceutical preparations containing the compositions are used for the control of bacteria responsible for disorders of the gastrointestinal tract.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: April 19, 1994
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter Blackburn, Steven J. Projan, Edward B. Goldberg
  • Nisin compositions for use as enhanced broad range bactericides
    Patent number: 5260271
    Abstract: Bacteriocin compositions comprising lanthionine containing bacteriocins and non-bactericidal agents. When the bacteriocin compositions are combined with a suitable carrier with each component present in sufficient quantities such that the composition is effective against Gram negative bacteria in addition to Gram positive bacteria, they become enhanced, rapid acting, broad range bactericides suitable for a variety of applications.
    Type: Grant
    Filed: April 17, 1992
    Date of Patent: November 9, 1993
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter Blackburn, June Polak, Sara-Ann Gusik, Stephen D. Rubino
  • Nisin compositions for use as enhanced, broad range bactericides
    Patent number: 5217950
    Abstract: Bacteriocin compositions comprising lanthionine containing bacteriocins and non-bactericidal agents. When the bacteriocin compositions are combined with a suitable carrier with each component present in sufficient quantities such that the composition is effective against Gram negative bacteria in addition to Gram positive bacteria, they become enhanced, rapid acting, broad range bactericides suitable for a variety of applications.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: June 8, 1993
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter Blackburn, June Polak, Sara-Ann Gusik, Stephen D. Rubino