Patents Assigned to Applied Protein Sciences, LLC
  • TGF-? polypeptides, functional fragments and methods of use therefor
    Patent number: 7329645
    Abstract: Disclosed are TGF-? polypeptides, related polypeptides, fragments and mimetics thereof useful in stimulating stem cell or precursor cell proliferation, migration and differentiation. The methods of the invention are useful to treat tissue injury as well as expand stem cell populations in, or obtained from, gastrointestinal, musculoskeletal, urogenital, neurological and cardiovascular tissues. The methods include ex vivo and in vivo applications.
    Type: Grant
    Filed: January 15, 2002
    Date of Patent: February 12, 2008
    Assignee: Applied Protein Sciences, LLC
    Inventors: Daniel R. Twardzik, Andre Pernet, Thomas S. Felker, Stefan Paskell