Patents Assigned to APTABHARAT INNOVATION PRIVATE LIMITED
  • APTAMER AGAINST M.TB MPT51 AND USES THEREOF
    Publication number: 20200283774
    Abstract: The invention provides single stranded DNA aptamers specific to M.tb MPT51 and uses thereof in rapid, robust, highly specific, and cost effective diagnosis of tuberculosis. The invention also provides methods and devices based on the aptamers of the invention for the diagnosis of tuberculosis. Advantageously, aptamers of the present invention can selectively detect as low as 2 ng of M.tb MPT51 and this activity remains unaltered in presence of anti-MPT51 antibodies. The developed device can give sample-to-answer within 30 minutes.
    Type: Application
    Filed: September 7, 2018
    Publication date: September 10, 2020
    Applicants: TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, APTABHARAT INNOVATION PRIVATE LIMITED
    Inventors: Tarun KUMAR SHARMA, Jaya SIVASWAMI TYAGI, Ritu DAS, Abhijeet DHIMAN