Patents Assigned to Apterna Limited
  • RNA aptamers against transferrin receptor (TfR)
    Patent number: 11427826
    Abstract: A ribonucleic acid compound is disclosed, the ribonucleic acid compound comprising, or consisting of, an RNA sequence having at least 90% sequence identity to SEQ ID NO: 1, wherein said RNA sequence has a length of 29 nucleotides or fewer, and wherein the RNA sequence is capable of binding to a transferrin receptor (TfR).
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: August 30, 2022
    Assignees: City of Hopw, Apterna Limited
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib
  • Bi-specific aptamer
    Patent number: 11219635
    Abstract: Provided are aptamers and aptamer compositions and particularly, although not exclusively, to a bi-specific aptamer capable of binding a tumor cell antigen and an immune cell surface protein.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: January 11, 2022
    Assignees: City of Hope, Apterna Limited
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib