Patents Assigned to Apterna Ltd
  • Patent number: 11236341
    Abstract: Provided herein, inter alia, are nucleic acid compounds capable of binding transferrin receptor on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: February 1, 2022
    Assignees: City of Hope, Apterna Ltd
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib
  • Patent number: 11180761
    Abstract: Provided herein, inter alia, are nucleic acid compounds capable of binding PDGFR-a on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: November 23, 2021
    Assignees: City of Hope, Apterna Ltd
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib
  • Patent number: 10550394
    Abstract: Provided herein, inter alia, are compounds capable of binding HSP70 (e.g. mHSP70) on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: February 4, 2020
    Assignees: CITY OF HOPE, APTERNA LTD
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib
  • Publication number: 20170226515
    Abstract: Provided herein, inter alia, are nucleic acid compounds capable of binding transferrin receptor on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.
    Type: Application
    Filed: October 15, 2015
    Publication date: August 10, 2017
    Applicants: City of Hope, Apterna Ltd
    Inventors: John J. Rossi, Sorah Yoon, Nagy Habib