Patents Assigned to Aptitude Medical Systems, Inc.
  • COMPOSITION AND METHOD FOR NUCLEIC ACID DETECTION
    Publication number: 20240167107
    Abstract: The present application provides compositions and methods for detecting a target nucleic acid in a sample. The present application also provides systems, isolated oligonucleotides, and kits for detecting a target nucleic acid in a sample.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 23, 2024
    Applicant: APTITUDE MEDICAL SYSTEMS, INC.
    Inventors: Jinpeng WANG, Hui KANG, Qin YANG, Brian Scott FERGUSON, Qiang GONG
  • Systems and methods for sample analysis
    Patent number: 11857962
    Abstract: The present disclosure provides systems and methods for sample analysis. The system comprises a container. The container comprises a sample receptacle and a cap, and the cap comprises a reservoir for retaining a composition, a first piercing member and a first pierceable barrier for sealing said composition within said reservoir. There is also provided a method for sample analysis.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: January 2, 2024
    Assignee: APTITUDE MEDICAL SYSTEMS, INC.
    Inventors: Brian Scott Ferguson, Wentao Shi, Hui Kang, Tyler Chozinski, Jinpeng Wang, Qiang Gong
  • Compositions, methods and systems for identifying candidate nucleic acid agent
    Patent number: 11248231
    Abstract: The present disclosure provides compositions, methods and systems for generating nucleic acid agents having a desired property, such as a property for specifically binding to a target. More specifically, the present disclosure provides compositions, methods and systems for generating a pool of modified members comprising modified nucleic acid agents with an unlimited range of chemical diversity.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: February 15, 2022
    Assignee: Aptitude Medical Systems, Inc.
    Inventors: Jinpeng Wang, Qin Yang, Qiang Gong
  • Methods and systems for identifying candidate nucleic acid agent
    Patent number: 11041849
    Abstract: The present disclosure provides methods, kits and compositions for identifying nucleic acid agents having a desired property, e.g., a property of specifically binding to a target (such as a protein target) with high affinity. More specifically, the present disclosure provides methods, kits and compositions for identifying candidate nucleic acid agents with both high specificity and affinity for a target.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: June 22, 2021
    Assignee: APTITUDE MEDICAL SYSTEMS, INC.
    Inventors: Jinpeng Wang, Brian Ferguson, Qiang Gong
  • USE OF NUCLEIC ACID AGENTS FOR ULTRA-SENSITIVE DIGITAL DETECTION AND QUANTIFICATION OF TARGET MOLECULES
    Publication number: 20160312265
    Abstract: Described herein are methods and systems for detecting and quantifying target molecules and particles in a sample using a plurality of capture objects and a plurality of detection objects. The methods and system utilize nucleic-acid aptamers and digital DNA amplification and detection technology to transform the analog signals obtained from conventional ELISA to digital signals from single molecule counting.
    Type: Application
    Filed: January 14, 2015
    Publication date: October 27, 2016
    Applicant: Aptitude Medical Systems, Inc.
    Inventors: Jinpeng Wang, Qiang Gong, B. Scott Ferguson