Patents Assigned to AQUESTIVE THERAPEUTICS, INC.
  • Patent number: 12171723
    Abstract: Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
    Type: Grant
    Filed: October 18, 2023
    Date of Patent: December 24, 2024
    Assignee: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Keith Kendall, Dan Barber, Theresa Wood, Peter Boyd, John Maxwell
  • Patent number: 12023309
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Grant
    Filed: June 8, 2022
    Date of Patent: July 2, 2024
    Assignee: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Publication number: 20240148673
    Abstract: Pharmaceutical compositions of epinephrine and its prodrugs are described, the prodrugs having a half-life of less than one minute, and the compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: January 16, 2024
    Publication date: May 9, 2024
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Publication number: 20240050317
    Abstract: Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
    Type: Application
    Filed: October 18, 2023
    Publication date: February 15, 2024
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Keith Kendall, Dan Barber, Theresa Wood, Peter Boyd, John Maxwell
  • Publication number: 20240016734
    Abstract: Pharmaceutical compositions of epinephrine and its prodrugs are described and the compositions having enhanced active component permeation properties are described as being administered with specific residence times.
    Type: Application
    Filed: June 14, 2023
    Publication date: January 18, 2024
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Publication number: 20230414452
    Abstract: Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
    Type: Application
    Filed: September 7, 2023
    Publication date: December 28, 2023
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Keith Kendall, Dan Barber, Theresa Wood, Peter Boyd, John Maxwell
  • Patent number: 11806311
    Abstract: Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: November 7, 2023
    Assignee: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Keith Kendall, Dan Barber, Theresa Wood, Peter Boyd, John Maxwell
  • Publication number: 20230149304
    Abstract: An oral film in an individual unit dose for delivery of one or more actives is disclosed herein, the film having a precisely calculated and controlled active dissolution profile. A wide variety of actives may be used, including, for example, clobazam, diazepam, or riluzole. Also disclosed are methods of treating a variety of diseases and conditions, for example, epilepsy and seizures, by administering the oral film disclosed herein.
    Type: Application
    Filed: November 17, 2022
    Publication date: May 18, 2023
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Stephen Wargacki, Vincent J. Buono, Susan Shumard, Christopher James Santee
  • Publication number: 20230145752
    Abstract: An oral film in an individual unit dose for delivery of one or more actives is disclosed herein, the film having a precisely calculated and controlled active dissolution profile. A wide variety of actives may be used, including, for example, clobazam, diazepam, or riluzole. Also disclosed are methods of treating a variety of diseases and conditions, for example, epilepsy and seizures, by administering the oral film disclosed herein.
    Type: Application
    Filed: December 30, 2022
    Publication date: May 11, 2023
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Stephen Wargacki, Vincent J. Buono, Susan Shumard, Christopher James Santee
  • Publication number: 20230138361
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: June 8, 2022
    Publication date: May 4, 2023
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Publication number: 20230130055
    Abstract: Soluble drug delivery films can exhibit an enhanced stability.
    Type: Application
    Filed: October 21, 2022
    Publication date: April 27, 2023
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Stephen Paul Wargacki, Rajesh Kumar Kainthan, Vincent Buono, Alexander Mark Schobel, Michael Koons, Michael Goodrich, Gregory Tsodikov
  • Publication number: 20230131450
    Abstract: A method of administering diazepam having a food effect is described.
    Type: Application
    Filed: October 25, 2022
    Publication date: April 27, 2023
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Stephen Paul Wargacki, Alexander Mark Schobel
  • Patent number: 11541002
    Abstract: An oral film in an individual unit dose for delivery of one or more actives is disclosed herein, the film having a precisely calculated and controlled active dissolution profile. A wide variety of actives may be used, including, for example, clobazam, diazepam, or riluzole. Also disclosed are methods of treating a variety of diseases and conditions, for example, epilepsy and seizures, by administering the oral film disclosed herein.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: January 3, 2023
    Assignee: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Stephen Wargacki, Vincent J. Buono, Susan Shumard, Christopher James Santee
  • Publication number: 20220233471
    Abstract: Systems and methods of delivering a drug product by inhalation can include a prodrug composition.
    Type: Application
    Filed: January 15, 2022
    Publication date: July 28, 2022
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark SCHOBEL, Daniel R. BARBER, Stephen Paul WARGACKI, Rajesh Kumar KAINTHAN, Stephanie M. VARJAN, Malarvizhi DURAI
  • Publication number: 20220160657
    Abstract: Pharmaceutical compositions of epinephrine and its prodrugs are described, the prodrugs having a half-life of less than one minute, and the compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: December 13, 2021
    Publication date: May 26, 2022
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Publication number: 20220088201
    Abstract: Film products, especially suitable for oral delivery, which can be formed during manufacture in the form of large and/or heavy film strips or sheets and subsequently cut into uniform dosage units, each dosage unit being uniform in content and having distributed therein a linear polysaccharide, such as pullulan, a plasticizer, and an active component.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 24, 2022
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Garry L. Myers, Michael Li, Beuford Arlie Bogue, Eric Dadey
  • Patent number: 11273131
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: March 15, 2022
    Assignee: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Publication number: 20220054426
    Abstract: The present invention relates to methods and apparatuses for forming an active-containing film product, while significantly reducing the amount of wasted active material. The resulting product is an active-containing film product that meets the user's predetermined criteria of physical properties and is suitable for use.
    Type: Application
    Filed: August 31, 2021
    Publication date: February 24, 2022
    Applicant: Aquestive Therapeutics, Inc.
    Inventor: Beuford A. Bogue
  • Patent number: 11207805
    Abstract: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: December 28, 2021
    Assignee: Aquestive Therapeutics, Inc.
    Inventors: Robert K. Yang, Richard C. Fuisz, Garry L. Myers, Joseph M. Fuisz
  • Patent number: 11191737
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: December 7, 2021
    Assignee: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki