Abstract: A method for metering and storing liquids by means of a permanently open container (1), wherein: the container (1) comprises a liquid reservoir (11) in which at least one liquid (2) is contained for storage; the container (1) has at least one opening (15) for the metered discharging of the liquid from the liquid reservoir (11); the opening (15) is permanently open; influencing factors affect at least one change in pressure (4) in the container (1); influencing factors render the system formed of the container (1) and liquid (2) unstable; the pressure (4) is detected in at least one location in the container (1); and, subject to at least one detected change in pressure (4), at least one reaction (9) is initiated that is suitable for maintaining the system of the container (1) and liquid (2) in a stable state or for re-establishing this stable state.
Type:
Grant
Filed:
March 2, 2018
Date of Patent:
April 5, 2022
Assignee:
Aquila Biolabs GmbH
Inventors:
Konrad Herzog, David Frank, Carsten Presser
Abstract: A method, a device, and a system for the automated determination of optical densities or of the change in optical densities of reaction mixtures in shaken reactors during shaking operation. The method uses a reaction mixture distribution, which periodically fluctuates because of the shaking action, to record measurement points (20/21) of transmission/scattered-light measurements. All measurement points (20/21) of a measurement operation are combined into a measurement series (34), from which the optical density and/or the change in the optical density, and other process parameters, can be determined with high reliability by means of suitable mathematical methods.
Abstract: A method for tuning optical measurements on continuously mixed reactors, wherein a content of the reactor has at least one optically detectable measured variable, which is carried out by at least one optical measuring arrangement, wherein at least one optical measurement is tuned to a form, distribution, or movement state of at least one phase of the reactor content, wherein mixing the reactor content causes local changes in the permittivity within the reactor, which is detected at at least one location having a known distance from the at least one optical measuring arrangement to be tuned based on a permittivity signal, and wherein the detected permittivity signal of at least one location having a known distance from the at least one optical measuring arrangement to be tuned is used to tune at least one optical measurement to the form, distribution, or movement state of the reactor content.