Patents Assigned to AQUILUS PHARMACEUTICALS, INC.
  • Compounds and methods for the treatment of pain and other diseases
    Patent number: 8765953
    Abstract: The present invention relates generally to alkyne containing pharmaceutical agents, and in particular, to phenylethynyl-thiophene based metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of MMP inhibiting compounds that exhibit increased potency, metabolic stability and/or reduced toxicity in relation to currently known MMP inhibitors for the treatment of pain and other diseases such as cancer. Additionally, the present invention relates to methods for treating pain in a patient comprising administering to the patient a pain-reducing effective amount of a present compound.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 1, 2014
    Assignee: Aquilus Pharmaceuticals, Inc.
    Inventor: Irving Sucholeiki
  • Compounds and methods for the treatment of pain and other diseases
    Patent number: 8530453
    Abstract: The present invention relates generally to pharmaceutical agents, and in particular, to metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of dual acting MMP-2 and MMP-9 inhibiting compounds that exhibit increased potency, metabolic stability and/or reduced toxicity in relation to currently known MMP-2 and MMP-9 inhibitors for the treatment of pain and other diseases. Additionally, the present invention relates to methods for treating pain, addiction and/or withdrawal symptoms in a patient comprising administering to the patient a pain-reducing effective amount of a present compound.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: September 10, 2013
    Assignee: Aquilus Pharmaceuticals, Inc.
    Inventor: Irving Sucholeiki
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES
    Publication number: 20110257222
    Abstract: The present invention relates generally to alkyne containing pharmaceutical agents, and in particular, to phenylethynyl-thiophene based metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of MMP inhibiting compounds that exhibit increased potency, metabolic stability and/or reduced toxicity in relation to currently known MMP inhibitors for the treatment of pain and other diseases such as cancer. Additionally, the present invention relates to methods for treating pain in a patient comprising administering to the patient a pain-reducing effective amount of a present compound.
    Type: Application
    Filed: December 21, 2009
    Publication date: October 20, 2011
    Applicant: AQUILUS PHARMACEUTICALS, INC.
    Inventor: Irving Sucholeiki