Abstract: The subject invention concerns a unit dose formulation comprising less than 2.5 mg of prednisolone or an equivalent, equipotent amount of another corticosteroid. One embodiment of a method of the invention concerns once daily administration of the unit dose formulation between midnight and 6 a.m. for the treatment of rheumatoid arthritis.
Type:
Grant
Filed:
October 1, 2002
Date of Patent:
January 13, 2004
Assignee:
Arakis, Ltd.
Inventors:
Hazel Judith Bardsley, Robin Mark Bannister, Julian Clive Gilbert
Abstract: The present invention pertains to a unit dose formulation comprising 0.25 to 2 mg of a corticosteroid. This small dose can be used to treat rheumatoid arthritis, especially if adapted to release at least 90% by weight of the corticosteroid, 2 to 8 hours after administration.