Abstract: This invention relates to a co-crystal of vorapaxar and aspirin. The inventive co-crystal antagonizes the PAR-1 receptor. This invention also provides for pharmaceutical compositions comprising the inventive co-crystal as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by antagonizing the PAR-1 receptor.
Type:
Grant
Filed:
July 17, 2014
Date of Patent:
March 28, 2017
Assignee:
ARALEZ PHARMACEUTICALS TRADING DAC
Inventors:
Scott Trzaska, Alicia V. Duran-Capece, Matthew Lamm