Abstract: The present invention relates generally to an immunotherapeutic composition. More particularly, the present invention relates to an immunotherapeutic composition which interacts immunologically with T lymphocytes in subjects having peanut allergy or allergy to other tree nuts. This composition is preferably immunointeractive with T cells in subjects having an allergy to the Ara h 1 and/or Ara h 2 allergens. The composition of the present invention is useful in the therapeutic or prophylactic treatment of conditions characterised by an aberrant, inappropriate or otherwise unwanted immune response to peanut, Ara h 1 and/or Ara h 2 or derivative or homologue thereof.
Type:
Grant
Filed:
September 25, 2014
Date of Patent:
March 8, 2022
Assignee:
ARAVAX PTY LTD
Inventors:
Robyn Elizabeth O'Hehir, Sara Rachel Prickett, Jennifer May Rolland
Abstract: The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with T lymphocytes in subjects having peanut allergy, or allergy to other tree nuts, and genetic sequences encoding same. These molecules are preferably immunointeractive with T cells in subjects having an allergy to the Ara h 1 allergen. The molecules of the present invention are useful in the development of diagnostic, therapeutic and prophylactic agents for conditions characterised by an aberrant, inappropriate or otherwise unwanted immune response to Ara h 1 or derivative or homologue thereof.
Type:
Grant
Filed:
October 30, 2013
Date of Patent:
August 24, 2021
Assignee:
ARAVAX PTY LTD
Inventors:
Robyn O'Hehir, Jennifer Rolland, Sara Prickett