Abstract: A cryosurgical instrument features a cryogen in liquid or liquid-gaseous (mist) form being supplied by a feeding lumen into the internal space of a cryotip at the distal end of the cryosurgical instrument. The distal section of the feeding lumen is helically coiled, so that an outer diameter of the helically coiled distal section fits an inner diameter of a cylindrical envelope of said cryotip, and said helically coiled distal section and said cylindrical envelope are in thermal contact.

Abstract: A cryoprobe for surgical and other treatments. The cryoprobe comprises an expandable section that performs displacement of a distal cryotip forwards when there is elevation of the operation pressure in the interior of the cryoprobe. Needle-wise metal elements are installed on the external side of the cryotip. These needle-wise elements are deflecting outwards by a deflecting member fastened on the distal edge of an external shaft of the cryoprobe. This allows a significant enlargement of the frozen volume of the treated tissue with the same operation temperature and the outer diameter of the cryoprobe. In another embodiment, the needle elements are formed in a displaceable metal sheath and a distal section of a cryotip and/or special protrusions on this distal section act as the deflecting member.

Abstract: A siphon for delivery of a liquid cryogen from a container such as a Dewar flask. The siphon ensures delivery of a liquid cryogen with a lower proportion of the gaseous fraction. The siphon comprises a central feeding conduit, which is largely contained within the Dewar flask. There is an auxiliary conduit surrounding the central feeding conduit; the outer upper section of this auxiliary conduit is provided with an adjustable valve intended to release a gaseous fraction of the cryogen contained in the annular gap between the auxiliary and central feeding conduits. The upper section of the central feeding conduit is provided with an external layer of a porous capillary coating or with a wick; this ensures that the upper section of the central feeding conduit is continuously wetted with the liquid cryogen. This porous capillary coating prevents gasification of the liquid cryogen in the central feeding conduit.

Abstract: The invention proposes a cryosurgical instrument and its accessory system operating on the base of a refrigerant evaporation. The invention comprises combination of some technical solutions. Flow in a central lumen of the cryosurgical instrument has oscillating character; the refrigerant is provided on the internal surface of the distal cryotip in the form of separated portions. 2. The internal surface of the distal cryotip of the cryosurgical instrument is covered by a porous coating, which soaks completely one portion of the refrigerant. 3. Vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are removed through the central lumen into the atmosphere. Combination of these technical solutions allows to construct a safely cryosurgical instrument with high freezing power and small outer diameter. The proposed cryosurgical instrument may be designed as a flexible cryocatheter or as a rigid cryoprobe.

Abstract: The invention proposes a cryosurgical instrument and its accessory system operating on the base of a refrigerant evaporation. The invention comprises combination of some technical solutions. Flow in a central lumen of the cryosurgical instrument has oscillating character; the refrigerant is provided on the internal surface of the distal cryotip in the form of separated portions. 2. The internal surface of the distal cryotip of the cryosurgical instrument is covered by a porous coating, which soaks completely one portion of the refrigerant. 3. Vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are removed through the central lumen into the atmosphere. Combination of these technical solutions allows to construct a safely cryosurgical instrument with high freezing power and small outer diameter. The proposed cryosurgical instrument may be designed as a flexible cryocatheter or as a rigid cryoprobe.

Abstract: A pumping unit for delivering a liquid medium from a low pressure vessel such that the delivered medium has sufficiently high pressure, by providing the liquid medium in the form of separated pulses.

Abstract: The invention proposes a cryosurgical instrument and its accessory system operating on the base of a refrigerant evaporation. The invention comprises combination of some technical solutions. Flow in a central lumen of the cryosurgical instrument has oscillating character; the refrigerant is provided on the internal surface of the distal cryotip in the form of separated portions. 2. The internal surface of the distal cryotip of the cryosurgical instrument is covered by a porous coating, which soaks completely one portion of the refrigerant. 3. Vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are removed through the central lumen into the atmosphere. Combination of these technical solutions allows to construct a safely cryosurgical instrument with high freezing power and small outer diameter. The proposed cryosurgical instrument may be designed as a flexible cryocatheter or as a rigid cryoprobe.

Abstract: A cryosurgical instrument, in which a separator is installed in a central feeding lumen and/or in a cryotip to separate gaseous and liquid components of a cryogen.

Abstract: The invention proposes a cryosurgical instrument and its accessory system operating on the base of a refrigerant evaporation. The invention comprises combination of some technical solutions. Flow in a central lumen of the cryosurgical instrument has oscillating character; the refrigerant is provided on the internal surface of the distal cryotip in the form of separated portions. 2. The internal surface of the distal cryotip of the cryosurgical instrument is covered by a porous coating, which soaks completely one portion of the refrigerant 3. Vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are removed through the central lumen into the atmosphere. Combination of these technical solutions allows to construct a safely cryosurgical instrument with high freezing power and small outer diameter. The proposed cryosurgical instrument may be designed as a flexible cryocatheter or as a rigid cryoprobe.

Abstract: The invention involves a siphon for delivery of a liquid cryogen from a container such as a Dewar flask. The siphon ensures delivery of a liquid cryogen with a lower proportion of the gaseous fraction. The siphon comprises a central feeding conduit, which is largely contained within the Dewar flask. There is an auxiliary conduit surrounding the central feeding conduit; the outer upper section of this auxiliary conduit is provided with an adjustable valve intended to release a gaseous fraction of the cryogen contained in the annular gap between the auxiliary and central feeding conduits. The upper section of the central feeding conduit is provided with an external layer of a porous capillary coating or with a wick; this ensures that the upper section of the central feeding conduit is continuously wetted with the liquid cryogen. This porous capillary coating prevents gasification of the liquid cryogen in the central feeding conduit.

Abstract: The invention proposes a cryoprobe for surgical and other treatments. The cryoprobe comprises a bellow-wise section that performs displacement of a distal cryotip forwards with elevation of operation pressure in the interior of the cryoprobe. Needle-wise metal elements are installed on the external side of the cryotip. These needle-wise elements are deflecting outwards by a deflecting member fastened on the distal edge of an external shaft of the cryoprobe. This allows to enlarge significantly a frozen volume of the treated tissue for same operation temperature and the outer diameter of the cryoprobe.

Abstract: For active thermal insulation of a cryoneedle or hyperthermia needle, preferably, the device comprises a needle for transmitting heat or cold, surrounded by a sheath for providing an opposing temperature to protect surrounding skin.

Abstract: A cryoprobe supports administration of an active agent to a location of cryogenic treatment. The cryoprobe may optionally be combined with a syringe to form a cryoprobe system; alternatively and optionally, the syringe may be external to the cryoprobe.

Abstract: A cryosurgical probe (cryoprobe) for ablation of a superficial tissue. The cryoprobe operation is preferably based on combination of two freezing effects: a) heat transfer from a liquid, gaseous or aerosolized cryogen, which is delivered from openings in the cryoprobe tip immediately on the surface of the treated tissue, and b) heat transfer from needle(s) installed on the outer surface of the cryotip. This needle (or needles) is constructed from material with high thermal conductivity. In addition, the outer surface of the cryotip may be provided with spacers, which limit the depth of penetration of the needle(s) into the tissue.

Abstract: The invention proposes a cryoprobe for surgical and other treatments. The cryoprobe comprises a bellow-wise section that performs displacement of a distal cryotip forwards with elevation of operation pressure in the interior of the cryoprobe. Needle-wise metal elements are installed on the external side of the cryotip. These needle-wise elements are deflecting outwards by a deflecting member fastened on the distal edge of an external shaft of the cryoprobe. This allows to enlarge significantly a frozen volume of the treated tissue for same operation temperature and the outer diameter of the cryoprobe.

Abstract: A cryoprobe for surgical and other treatments. The cryoprobe comprises an expandable section that performs displacement of a distal cryotip forwards when there is elevation of the operation pressure in the interior of the cryoprobe. Needle-wise metal elements are installed on the external side of the cryotip. These needle-wise elements are deflecting outwards by a deflecting member fastened on the distal edge of an external shaft of the cryoprobe. This allows a significant enlargement of the frozen volume of the treated tissue with the same operation temperature and the outer diameter of the cryoprobe. In another embodiment, the needle elements are formed in a displaceable metal sheath and a distal section of a cryotip and/or special protrusions on this distal section act as the deflecting member.

Abstract: The invention proposes a cryosurgical instrument and its accessory system operating on the base of a refrigerant evaporation. The invention comprises combination of some technical solutions. Flow in a central lumen of the cryosurgical instrument has oscillating character; the refrigerant is provided on the internal surface of the distal cryotip in the form of separated portions. 2. The internal surface of the distal cryotip of the cryosurgical instrument is covered by a porous coating, which soaks completely one portion of the refrigerant. 3. Vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are removed through the central lumen into the atmosphere. Combination of these technical solutions allows to construct a safely cryosurgical instrument with high freezing power and small outer diameter. The proposed cryosurgical instrument may be designed as a flexible cryocatheter or as a rigid cryoprobe.

Abstract: The invention is directed to a cryosurgical instrument and to an accessory system operating on the base of refrigerant evaporation, wherein the portions of the refrigerant are periodically provided to the distal cryotip of the cryosurgical instrument via a central lumen thereof. The internal surface of the distal cryotip is preferably covered by a porous coating capable of soaking at least one portion of the refrigerant. The vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are preferably removed through the central lumen of the cryosurgical instrument into the atmosphere. These features may be combined to construct a cryosurgical instrument with relatively high freezing power and small outer diameter which may be designed as a flexible cryocatheter or alternatively as a rigid cryoprobe.