Publication number: 20240075089
Abstract: The present disclosure provides botanicals and/or biotin or analogs thereof, that proliferate or reduce stem cell populations and activate or attenuate Wat/?-Catenin signaling and thus treat or prevent diseases related to signal transduction. In particular, the disclosure provides Botanicals and Biotin or analogs thereof, that proliferate or reduce stem cell populations and activate or attenuate Wnt/?-Catenin signaling in tissues expressing Wnt1OB including, adipose, adrenal, artery, blood, bone marrow, brain, breast, cervix, colon, esophagus, heart, intestine, kidney, liver, lung, muscle, ovary, pituitary, prostate, skin, spleen, testis, thyroid, uterus and vagina. The present compositions and methods are particularly suited to growing and melanizing hair.
Type:
Application
Filed:
December 30, 2020
Publication date:
March 7, 2024
Applicant:
Arbor Life Holdings, Ltd.
Inventors:
Peter R. Feldman, Luciano E. Marra, Dennis M. Brown, Deborah J. Cahan