Patents Assigned to Arc Bio, LLC
  • Patent number: 11929149
    Abstract: Provided herein are methods for aligning raw genetic sequence data generated by a sequencing device. Also provided herein are methods and systems for quantifying the probability that possible alignments for one or more read pairs are correct, for calling known variants, and for detecting novel structural variants.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: March 12, 2024
    Assignee: ARC BIO, LLC
    Inventors: Alejandro Quiroz Zarate, Roberto Olivares-Amaya, Thomas James Watson, Jr., Helen Cecile Van Aggelen, Eduardo Coronado Sroka, Carlos Antonio Angulo Sermeno, Fernando Fimbres Jurado, Abraham Solis Garcia-Inda, Fernando Fontove Herrera, Pablo G. Coste
  • Patent number: 11789906
    Abstract: Method and systems for preparing and analyzing a DNA sample from a subject are provided herein. Also provided are methods and systems for obtaining, analyzing, and manipulating genomic and proteomic sequence data. In particular, methods and systems provided herein involve transformation of raw genetic or proteomic sequence into a compressed data set and transmission of the compressed data set using a fixed binary encoding scheme capable of compressing the data by up to 75%. An interface is in communication with the compression module and configured to display transmitted genomic and proteomic sequence data.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: October 17, 2023
    Assignee: ARC BIO, LLC
    Inventors: Roberto Olivares-Amaya, David Andrew Sinclair, Alejandro Quiroz-Zarate, Thomas J. Watson, Jr.
  • Patent number: 11692213
    Abstract: Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sample, and/or partitioning of sequences from a sample. The methods and compositions are applicable to biological, clinical, forensic, and environmental samples.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: July 4, 2023
    Assignee: ARC BIO, LLC
    Inventors: Meredith L. Carpenter, Carlos D. Bustamante, Stephane B. Gourguechon
  • Patent number: 11405371
    Abstract: A device for compressing subject data. the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: August 2, 2022
    Assignee: ARC BIO, LLC
    Inventors: Jason Michael Anderson, David A Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Ricardo Godinez-Moreno
  • Patent number: 11122017
    Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: September 14, 2021
    Assignee: ARC BIO, LLC
    Inventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, Jr., Jason Michael Anderson, Pablo G. Coste
  • Patent number: 10787662
    Abstract: Provided herein are methods and compositions to make guide nucleic acids (gNAs), nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs from any source nucleic acid. Also provided herein are methods and compositions to use the resulting gNAs, nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs in a variety of applications.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: September 29, 2020
    Assignee: ARC BIO, LLC
    Inventor: Stephane B. Gourguechon
  • Patent number: 10774365
    Abstract: Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sample, and/or partitioning of sequences from a sample. The methods and compositions are applicable to biological, clinical, forensic, and environmental samples.
    Type: Grant
    Filed: December 19, 2015
    Date of Patent: September 15, 2020
    Assignee: ARC BIO, LLC
    Inventors: Meredith L. Carpenter, Carlos D. Bustamante, Stephane B. Gourguechon
  • Publication number: 20200190508
    Abstract: Provided herein are methods and compositions to make guide nucleic acids (gNAs), nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs from any source nucleic acid. Also provided herein are methods and compositions to use the resulting gNAs, nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs in a variety of applications.
    Type: Application
    Filed: June 7, 2018
    Publication date: June 18, 2020
    Applicants: Arc Bio, LLC, Arc Bio, LLC
    Inventors: Stephane B. GOURGUECHON, Meredith L. CARPENTER, Morten RASMUSSEN, Srihari RADHAKRISHNAN, Anna Katharina ELMER
  • Patent number: 10673826
    Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: June 2, 2020
    Assignee: ARC BIO, LLC
    Inventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, Jr., Jason Michael Anderson, Pablo G. Coste
  • Patent number: 10669571
    Abstract: Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sample, and/or partitioning of sequences from a sample. The methods and compositions are applicable to biological, clinical, forensic, and environmental samples.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 2, 2020
    Assignee: Arc Bio, LLC
    Inventors: Meredith L. Carpenter, Carlos D. Bustamante, Stephane B. Gourguechon
  • Patent number: 10630812
    Abstract: A device for compressing subject data, the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: April 21, 2020
    Assignee: ARC BIO, LLC
    Inventors: Jason Michael Anderson, David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Ricardo Godinez-Moreno
  • Patent number: 10538758
    Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: January 21, 2020
    Assignee: Arc Bio, LLC
    Inventors: Stephane B. Gourguechon, Eric Harness, David Sinclair, Meredith L. Carpenter
  • Publication number: 20190139628
    Abstract: The present disclosure provides techniques for analysis of genetic features. In particular, machine learning techniques can be used to analyze various statistical features in determining genetic features such as variants, markers, and traits, for example in a nucleotide sequence.
    Type: Application
    Filed: April 26, 2017
    Publication date: May 9, 2019
    Applicant: Arc Bio, LLC
    Inventors: Thomas J. Watson, Jr., Alejandro Quiroz Zarate
  • Publication number: 20180312830
    Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.
    Type: Application
    Filed: August 18, 2016
    Publication date: November 1, 2018
    Applicant: Arc Bio, LLC
    Inventors: Stephane B. GOURGUECHON, Eric HARNESS, David SINCLAIR, Meredith L. CARPENTER