Patents Assigned to Arc Bio, LLC
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Patent number: 11929149Abstract: Provided herein are methods for aligning raw genetic sequence data generated by a sequencing device. Also provided herein are methods and systems for quantifying the probability that possible alignments for one or more read pairs are correct, for calling known variants, and for detecting novel structural variants.Type: GrantFiled: August 4, 2016Date of Patent: March 12, 2024Assignee: ARC BIO, LLCInventors: Alejandro Quiroz Zarate, Roberto Olivares-Amaya, Thomas James Watson, Jr., Helen Cecile Van Aggelen, Eduardo Coronado Sroka, Carlos Antonio Angulo Sermeno, Fernando Fimbres Jurado, Abraham Solis Garcia-Inda, Fernando Fontove Herrera, Pablo G. Coste
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Patent number: 11789906Abstract: Method and systems for preparing and analyzing a DNA sample from a subject are provided herein. Also provided are methods and systems for obtaining, analyzing, and manipulating genomic and proteomic sequence data. In particular, methods and systems provided herein involve transformation of raw genetic or proteomic sequence into a compressed data set and transmission of the compressed data set using a fixed binary encoding scheme capable of compressing the data by up to 75%. An interface is in communication with the compression module and configured to display transmitted genomic and proteomic sequence data.Type: GrantFiled: November 19, 2015Date of Patent: October 17, 2023Assignee: ARC BIO, LLCInventors: Roberto Olivares-Amaya, David Andrew Sinclair, Alejandro Quiroz-Zarate, Thomas J. Watson, Jr.
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Patent number: 11692213Abstract: Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sample, and/or partitioning of sequences from a sample. The methods and compositions are applicable to biological, clinical, forensic, and environmental samples.Type: GrantFiled: August 3, 2020Date of Patent: July 4, 2023Assignee: ARC BIO, LLCInventors: Meredith L. Carpenter, Carlos D. Bustamante, Stephane B. Gourguechon
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Patent number: 11405371Abstract: A device for compressing subject data. the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.Type: GrantFiled: January 24, 2020Date of Patent: August 2, 2022Assignee: ARC BIO, LLCInventors: Jason Michael Anderson, David A Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Ricardo Godinez-Moreno
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Patent number: 11122017Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.Type: GrantFiled: May 19, 2020Date of Patent: September 14, 2021Assignee: ARC BIO, LLCInventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, Jr., Jason Michael Anderson, Pablo G. Coste
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Patent number: 10787662Abstract: Provided herein are methods and compositions to make guide nucleic acids (gNAs), nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs from any source nucleic acid. Also provided herein are methods and compositions to use the resulting gNAs, nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs in a variety of applications.Type: GrantFiled: December 7, 2016Date of Patent: September 29, 2020Assignee: ARC BIO, LLCInventor: Stephane B. Gourguechon
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Patent number: 10774365Abstract: Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sample, and/or partitioning of sequences from a sample. The methods and compositions are applicable to biological, clinical, forensic, and environmental samples.Type: GrantFiled: December 19, 2015Date of Patent: September 15, 2020Assignee: ARC BIO, LLCInventors: Meredith L. Carpenter, Carlos D. Bustamante, Stephane B. Gourguechon
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Publication number: 20200190508Abstract: Provided herein are methods and compositions to make guide nucleic acids (gNAs), nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs from any source nucleic acid. Also provided herein are methods and compositions to use the resulting gNAs, nucleic acids encoding gNAs, collections of gNAs, and nucleic acids encoding for a collection of gNAs in a variety of applications.Type: ApplicationFiled: June 7, 2018Publication date: June 18, 2020Applicants: Arc Bio, LLC, Arc Bio, LLCInventors: Stephane B. GOURGUECHON, Meredith L. CARPENTER, Morten RASMUSSEN, Srihari RADHAKRISHNAN, Anna Katharina ELMER
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Patent number: 10673826Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.Type: GrantFiled: February 9, 2016Date of Patent: June 2, 2020Assignee: ARC BIO, LLCInventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, Jr., Jason Michael Anderson, Pablo G. Coste
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Patent number: 10669571Abstract: Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sample, and/or partitioning of sequences from a sample. The methods and compositions are applicable to biological, clinical, forensic, and environmental samples.Type: GrantFiled: December 21, 2018Date of Patent: June 2, 2020Assignee: Arc Bio, LLCInventors: Meredith L. Carpenter, Carlos D. Bustamante, Stephane B. Gourguechon
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Patent number: 10630812Abstract: A device for compressing subject data, the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.Type: GrantFiled: February 5, 2015Date of Patent: April 21, 2020Assignee: ARC BIO, LLCInventors: Jason Michael Anderson, David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Ricardo Godinez-Moreno
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Patent number: 10538758Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.Type: GrantFiled: August 18, 2016Date of Patent: January 21, 2020Assignee: Arc Bio, LLCInventors: Stephane B. Gourguechon, Eric Harness, David Sinclair, Meredith L. Carpenter
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Publication number: 20190139628Abstract: The present disclosure provides techniques for analysis of genetic features. In particular, machine learning techniques can be used to analyze various statistical features in determining genetic features such as variants, markers, and traits, for example in a nucleotide sequence.Type: ApplicationFiled: April 26, 2017Publication date: May 9, 2019Applicant: Arc Bio, LLCInventors: Thomas J. Watson, Jr., Alejandro Quiroz Zarate
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Publication number: 20180312830Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.Type: ApplicationFiled: August 18, 2016Publication date: November 1, 2018Applicant: Arc Bio, LLCInventors: Stephane B. GOURGUECHON, Eric HARNESS, David SINCLAIR, Meredith L. CARPENTER