Patents Assigned to Arcedi Biotech ApS
  • Isolation of fetal cells using FACS
    Patent number: 11573229
    Abstract: The present invention relates to automated methods for isolating fetal cells from a sample, such as a blood sample, derived from a pregnant woman. The isolated fetal cells can be used for identifying genetic abnormalities in the fetal DNA.
    Type: Grant
    Filed: February 23, 2021
    Date of Patent: February 7, 2023
    Assignee: Arcedi Biotech ApS
    Inventors: Bolette Hestbek Nicolaisen, David Mathias Martin Leiding Kolvraa, Inga Baasch Christensen, Katarina Ravn, Line Dahl Jeppesen, Lotte Hatt, Palle Scheide Jensen, Ripudaman Singh
  • Enrichment and identification of fetal cells in maternal blood and ligands for such use
    Patent number: 9429520
    Abstract: The present invention relates to enrichment and/or identification of fetal cells of a maternal blood sample using fetal cell specific ligands and/or fetal cell specific hybridization probes wherein the ligand or probes are directed to an endothelial/mesenchymal marker, e.g. CD105, CD146 or CD141, in a first round of enrichment and the ligand or probes, in a second round of enrichment, are directed to an epithelial marker, e.g. a cytokeratin, such as CK7, CK8, CK18 or CK19. Enriched or identified fetal cells may be subjected to steps of detection or diagnosis, wherefore the present invention enables non-invasive 5 prenatal diagnostics.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: August 30, 2016
    Assignee: Arcedi Biotech ApS
    Inventors: Andreas Eckelt, Britta Christensen, Steen Kolvraa, Marie Brinch, Ripudaman Singh, Lotte Hatt