Patents Assigned to ARCH BIOPHYSICS, INC.
  • Surface coated structures and methods
    Patent number: 9422450
    Abstract: The present invention relates to a methods and composition in which a D-form or retro-inverso Pseudomonas pilin peptide, optionally having a polyethylene glycol moiety covalently attached to the peptide, is bound to a substrate. The disclosed methods and composition are useful for reducing the frictional coefficient, inhibiting biofilm formation by non-Pseudomonas bacteria, for reducing the inflammatory response to a material, for reducing corrosion of metals, and in biosensor applications.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 23, 2016
    Assignee: ARCH BIOPHYSICS, INC.
    Inventors: Randall Thomas Irvin, Elisabeth Melika Davis, Dongyang Li, Daniel Abraham Muruve
  • Surface Coated Structures and Methods
    Publication number: 20140220368
    Abstract: The present invention relates to a methods and composition in which a D-form or retro-inverso Pseudomonas pilin peptide, optionally having a polyethylene glycol moiety covalently attached to the peptide, is bound to a substrate. The disclosed methods and composition are useful for reducing the frictional coefficient, inhibiting biofilm formation by non-Pseudomonas bacteria, for reducing the inflammatory response to a material, for reducing corrosion of metals, and in biosensor applications.
    Type: Application
    Filed: April 13, 2012
    Publication date: August 7, 2014
    Applicant: ARCH BIOPHYSICS, INC.
    Inventors: Randall Thomas Irvin, Elisabeth Melika Davis, Gongyang Li, Daniel Abraham Muruve
  • SURFACE-COATED STRUCTURES AND METHODS
    Publication number: 20110293684
    Abstract: The present invention relates to a methods and composition in which a D-form or retro-inverso Pseudomonas pilin peptide is bound to a substrate. The disclosed methods and composition are useful for inhibiting biofilm formation by non-Pseudomonas bacteria, for reducing the inflammatory response to a material, for reducing corrosion of metals, and in biosensor applications.
    Type: Application
    Filed: April 14, 2011
    Publication date: December 1, 2011
    Applicant: ARCH BIOPHYSICS, INC.
    Inventors: Randall T. Irvin, Elisabeth M. Davis, DongYang Li, Daniel Abraham Muruve
  • SURFACE-COATED STRUCTURES AND METHODS
    Publication number: 20110087321
    Abstract: The present invention relates to a method for covalently attaching a compound to a stainless steel, tin, iron, or titanium substrate, by contacting exposed surface(s) of the substrate with a synthetic pilin peptide containing a disulfide loop derived from the C-terminal receptor binding protein of Type IV P. aeruginosa (T4P) pilin, to bind the pilin peptide to the exposed surface(s), and covalently attaching the compound to the pilin peptide. Also disclosed are a substrate formed by the method and a biosensor device that uses the uses. Also disclosed are methods for improving the corrosion resistance, adhesive force, hardness and electron work function of certain metals.
    Type: Application
    Filed: October 7, 2010
    Publication date: April 14, 2011
    Applicant: ARCH BIOPHYSICS, INC.
    Inventors: RANDALL T. IRVIN, ELISABETH M. DAVIS, DONGYANG LI