Patents Assigned to Arch Biosurgery, Inc.
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Patent number: 10869907Abstract: Meshes for use to control the movement of bodily fluids, such as blood, are described herein. The mesh can be partially or completely biodegradable or non-biodegradable. In one embodiment, the mesh is formed from one or more self-assembling peptides. The peptides can be in the form of fibers, such as nanofibers. The peptides can be assembled prior to formation of the mesh or after the mesh has been formed but before it is applied. Alternatively, the mesh can be prepared from unassembled peptides, which assemble at the time of application. The peptides can assemble upon contact with bodily fluids (e.g., blood) or can be contacted with an ionic solution to initiate assembly.Type: GrantFiled: April 25, 2019Date of Patent: December 22, 2020Assignee: ARCH BIOSURGERY, INC.Inventors: Terrence Norchi, Steven Kates, Rutledge Ellis-Behnke
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Patent number: 10682386Abstract: A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions. In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendrimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.Type: GrantFiled: September 26, 2017Date of Patent: June 16, 2020Assignee: Arch Biosurgery, Inc.Inventors: Rutledge Ellis-Behnke, Terrence W. Norchi, Stephen Richard Kelly
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Patent number: 10314886Abstract: Meshes for use to control the movement of bodily fluids, such as blood, are described herein. The mesh can be partially or completely biodegradable or non-biodegradable. In one embodiment, the mesh is formed from one or more self-assembling peptides. The peptides can be in the form of fibers, such as nanofibers. The peptides can be assembled prior to formation of the mesh or after the mesh has been formed but before it is applied. Alternatively, the mesh can be prepared from unassembled peptides, which assemble at the time of application. The peptides can assemble upon contact with bodily fluids (e.g., blood) or can be contacted with an ionic solution to initiate assembly.Type: GrantFiled: November 20, 2017Date of Patent: June 11, 2019Assignee: Arch Biosurgery, inc.Inventors: Terrence Norchi, Steven Kates, Rutledge Ellis-Behnke
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Patent number: 9821022Abstract: Meshes for use to control the movement of bodily fluids, such as blood, are described herein. The mesh can be partially or completely biodegradable or non-biodegradable. In one embodiment, the mesh is formed from one or more self-assembling peptides. The peptides can be in the form of fibers, such as nanofibers. The peptides can be assembled prior to formation of the mesh or after the mesh has been formed but before it is applied. Alternatively, the mesh can be prepared from unassembled peptides, which assemble at the time of application. The peptides can assemble upon contact with bodily fluids (e.g., blood) or can be contacted with an ionic solution to initiate assembly.Type: GrantFiled: May 16, 2016Date of Patent: November 21, 2017Assignee: Arch Biosurgery, Inc.Inventors: Terrence Norchi, Steven Kates, Rutledge Ellis-Behnke
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Patent number: 9789157Abstract: A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions. In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.Type: GrantFiled: October 16, 2015Date of Patent: October 17, 2017Assignee: Arch Biosurgery, Inc.Inventors: Rutledge Ellis-Behnke, Terrence W. Norchi, Stephen Richard Kelly
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Patent number: 9415084Abstract: Self assembling peptides and peptidomimetics can be utilized for the treatment and support of disorders associated with leaky or damaged tight junction and weak, diseased, or injured extracellular matrix. The self-assembling materials generally have alternating hydrophilic or hydrophobic residues or hydrophobic and/or hydrophilic sections which allow the material to react or interact with the glycoproteins found in the ECM. Diseases in which treatment with these materials applied to or near the site in need of treatment include diabetic retinopathy, sepsis, burns, and certain neurodegenerative diseases such as Parkinson's and Alzheimer's. The formulations can be administered by injection, spraying, topically or by catheter or via a wound dressing or other material to which it is applied and then applied to the site in need of treatment.Type: GrantFiled: March 14, 2008Date of Patent: August 16, 2016Assignee: Arch Biosurgery, Inc.Inventors: Rutledge Ellis-Behnke, Terrence W. Norchi, Stephen Richard Kelly
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Patent number: 9339476Abstract: Meshes for use to control the movement of bodily fluids, such as blood, are described herein. The mesh can be partially or completely biodegradable or non-biodegradable. In one embodiment, the mesh is formed from one or more self-assembling peptides. The peptides can be in the form of fibers, such as nanofibers. The peptides can be assembled prior to formation of the mesh or after the mesh has been formed but before it is applied. Alternatively, the mesh can be prepared from unassembled peptides, which assemble at the time of application. The peptides can assemble upon contact with bodily fluids (e.g., blood) or can be contacted with an ionic solution to initiate assembly.Type: GrantFiled: August 22, 2014Date of Patent: May 17, 2016Assignee: Arch Biosurgery, Inc.Inventors: Terrence Norchi, Steven Kates, Rutledge Ellis-Behnke
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Patent number: 9162005Abstract: A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions. In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.Type: GrantFiled: April 25, 2007Date of Patent: October 20, 2015Assignee: Arch Biosurgery, Inc.Inventors: Rutledge Ellis-Behnke, Terrence Norchi, Stephen Richard Kelly