Patents Assigned to Archimica S.r.l.
  • Publication number: 20130095149
    Abstract: The present invention relates to a process for the preparation of controlled-release solid oral pharmaceutical formulations of oxcarbazepine, and the pharmaceutical formulations obtainable by said process.
    Type: Application
    Filed: December 3, 2012
    Publication date: April 18, 2013
    Applicant: ARCHIMICA S.R.L.
    Inventor: Archimica S.R.L.
  • Patent number: 8367868
    Abstract: The present invention relates to a process for the synthesis of aryloxypropylamine and heteroaryloxypropylamine of formula I: where: A is aryl or heteroaryl, where the aryl is preferably a phenyl, optionally substituted, selected from benzyl and tolyl and the heteroaryl is preferably thiophenyl; Y is an aryl, preferably phenyl, a substituted phenyl or a naphthyl, where the substituted phenyl is preferably selected from tolyl, trihalomethyltolyl and alkoxytolyl, starting from a suitable amino alcohol of formula II:
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: February 5, 2013
    Assignee: Archimica S.r.l.
    Inventors: Giorgio Bertolini, Barbara Verzola, Domenico Vergani
  • Patent number: 7939660
    Abstract: A novel process for preparing emtricitabine, and more particularly a process for preparing emtricitabine involving the formation and isolation of intermediate compounds in salified form, is described.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: May 10, 2011
    Assignee: Archimica S.r.l.
    Inventors: Giorgio Bertolini, Maurizio Deleo, Marco Frigerio, Massimo Losa, Maurizio Velati
  • Patent number: 7858779
    Abstract: Process for preparing oxcarbazepine according to the steps of chlorocarbonylating (a), ammonolysis (b), and deprotecting (c). The invention is characterized by the use of triphosgene as chlorocarbonylating agent in step a).
    Type: Grant
    Filed: February 21, 2005
    Date of Patent: December 28, 2010
    Assignee: Archimica S.r.l.
    Inventors: Aldo Banfi, Deborah Bollini, Maurizio Serra, Gianluca Di Lernia
  • Publication number: 20100226944
    Abstract: The present invention relates to a process for the preparation of controlled-release solid oral pharmaceutical formulations of oxcarbazepine, and the pharmaceutical formulations obtainable by said process.
    Type: Application
    Filed: July 23, 2008
    Publication date: September 9, 2010
    Applicant: ARCHIMICA S.R.L.
    Inventors: Giovanni Sanso', Aldo Banfi, Giorgio Bertolini, Claudio Silva
  • Patent number: 7534885
    Abstract: A process is disclosed for the stereo-selective preparation of emtricitabine, which allows the desired product to be obtained in good yield and without the use of chromatographic techniques. The process for the production of emtricitabine of the formula (Ia) is characterized by the formation and isolation of intermediate compounds of formula (XIa) in salified form. Emtricitabine is a known antiviral drug.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: May 19, 2009
    Assignee: Archimica S.r.l.
    Inventors: Giorgio Bertolini, Maurizio Deleo, Marco Frigerio, Massimo Losa, Maurizio Velati
  • Patent number: 7285660
    Abstract: A process for the preparation of L-ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: October 23, 2007
    Assignee: Archimica S.r.l.
    Inventors: Aldo Banfi, Bruno Dall'Oro, Marco Frigerio, Alfredo Mancini
  • Patent number: 7285659
    Abstract: A process for the preparation of ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid. Said process comprises: a) the reaction of a triazole of the formula ?with a protected ribofuranose of the formula b) the removal of the Pg groups and, optionally, the conversion into a carboxyamide group of the R2 group of the compound obtained of the formula ?DD/mac—01.07.02.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: October 23, 2007
    Assignee: Archimica S.r.l.
    Inventors: Aldo Banfi, Bruno Dall'Oro, Marco Frigerio, Alfredo Mancini